Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis
Manisha Agarwal
1
,
Rupesh Agrawal
2, 3, 4
,
Neha Khandelwal
2
,
Alessandro Invernizzi
5
,
Kanika Aggarwal
1
,
Aman Sharma
6
,
Ramandeep Singh
1
,
Reema Bansal
1
,
Kusum Sharma
7
,
Nirbhai Singh
1
,
VISHALI GUPTA
1
1
3
4
Moorfields Eye Hospital, NHS Foundation Trust, London, UK
|
5
Publication type: Journal Article
Publication date: 2017-10-11
scimago Q2
wos Q2
SJR: 0.805
CiteScore: 4.6
Impact factor: 2.0
ISSN: 09273948, 17445078
PubMed ID:
29020533
Immunology and Allergy
Ophthalmology
Abstract
To assess choroidal vascular changes among patients with tubercular multifocal serpiginoid choroiditis (TB MSC) using previously validated techniques.Patients with TB MSC (n = 18) and healthy controls (n = 30) underwent enhanced-depth imaging optical coherence tomography (EDI-OCT) imaging. Using previously validated algorithm of image binarization, EDI-OCT scans were segmented to derive total choroidal area, luminal area, stromal area, and choroidal vascularity index (CVI).There was a statistically significant difference in the CVI between controls (66.90 ± 1.77%) and TB MSC patients (65.46 ± 2.53%; p < 0.001). There was significant reduction in CVI at follow-up (3 months) (63.77 ± 3.91%; p = 0.05). The choroidal thickness was higher in TB MSC compared to controls (278.90 ± 57.84 µm versus 329.33 ± 27.69 µm; p = 0.001).CVI provides insight into structural changes in choroid in TB MSC. During the active disease, there is relative decrease in choroidal vascularity. As the lesions heal, choriocapillaris atrophy occurs with remodeling of choroid.
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Total citations:
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Citations from 2024:
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(19.57%)
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GOST
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Agarwal M. et al. Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis // Ocular Immunology and Inflammation. 2017. Vol. 26. No. 6. pp. 838-844.
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Agarwal M., Agrawal R., Khandelwal N., Invernizzi A., Aggarwal K., Sharma A., Singh R., Bansal R., Sharma K., Singh N., GUPTA V. Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis // Ocular Immunology and Inflammation. 2017. Vol. 26. No. 6. pp. 838-844.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1080/09273948.2017.1370650
UR - https://doi.org/10.1080/09273948.2017.1370650
TI - Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis
T2 - Ocular Immunology and Inflammation
AU - Agarwal, Manisha
AU - Agrawal, Rupesh
AU - Khandelwal, Neha
AU - Invernizzi, Alessandro
AU - Aggarwal, Kanika
AU - Sharma, Aman
AU - Singh, Ramandeep
AU - Bansal, Reema
AU - Sharma, Kusum
AU - Singh, Nirbhai
AU - GUPTA, VISHALI
PY - 2017
DA - 2017/10/11
PB - Taylor & Francis
SP - 838-844
IS - 6
VL - 26
PMID - 29020533
SN - 0927-3948
SN - 1744-5078
ER -
Cite this
BibTex (up to 50 authors)
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@article{2017_Agarwal,
author = {Manisha Agarwal and Rupesh Agrawal and Neha Khandelwal and Alessandro Invernizzi and Kanika Aggarwal and Aman Sharma and Ramandeep Singh and Reema Bansal and Kusum Sharma and Nirbhai Singh and VISHALI GUPTA},
title = {Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis},
journal = {Ocular Immunology and Inflammation},
year = {2017},
volume = {26},
publisher = {Taylor & Francis},
month = {oct},
url = {https://doi.org/10.1080/09273948.2017.1370650},
number = {6},
pages = {838--844},
doi = {10.1080/09273948.2017.1370650}
}
Cite this
MLA
Copy
Agarwal, Manisha, et al. “Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis.” Ocular Immunology and Inflammation, vol. 26, no. 6, Oct. 2017, pp. 838-844. https://doi.org/10.1080/09273948.2017.1370650.