Taylor & Francis
Synthetic Communications
,  страницы 1-11

Straightforward synthesis of novel spiroether derivatives

Тип публикации: Journal Article
Дата публикации: 2021-04-07
Taylor & Francis
scimago Q3
wos Q3
БС2
SJR: 0.322
CiteScore: 4.3
Impact factor: 1.8
ISSN: 00397911, 15322432
Organic Chemistry
Краткое описание
Abstract We report the first full synthesis of novel spiroether derivatives via reaction of 4-oxobut-2-enoates and alloxan. Our synthesis features the single-step assembly, mild reaction conditions, good yields, high diastereoselectivity, operational simplicity, and the absence of tedious separation procedures. Most of the prepared compounds possessed moderate growth inhibitory effects on human alveolar adenocarcinoma (A549), malignant melanoma (A375), ovarian adenocarcinoma (SK-OV-3), and fibrosarcoma (HT-1080) cell lines. Graphical Abstract
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Bobrovskaya O. V. et al. Straightforward synthesis of novel spiroether derivatives // Synthetic Communications. 2021. pp. 1-11.
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Bobrovskaya O. V., Russkih A. A., Yankin A. N., Dmitriev M. V., Bunev A. S., Gein V. L. Straightforward synthesis of novel spiroether derivatives // Synthetic Communications. 2021. pp. 1-11.
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TY - JOUR
DO - 10.1080/00397911.2021.1903930
UR - https://www.tandfonline.com/doi/full/10.1080/00397911.2021.1903930
TI - Straightforward synthesis of novel spiroether derivatives
T2 - Synthetic Communications
AU - Bobrovskaya, Olga V
AU - Russkih, Aleksandr A
AU - Yankin, Andrey N
AU - Dmitriev, Maksim V
AU - Bunev, Alexander S.
AU - Gein, V L
PY - 2021
DA - 2021/04/07
PB - Taylor & Francis
SP - 1-11
SN - 0039-7911
SN - 1532-2432
ER -
BibTex
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@article{2021_Bobrovskaya,
author = {Olga V Bobrovskaya and Aleksandr A Russkih and Andrey N Yankin and Maksim V Dmitriev and Alexander S. Bunev and V L Gein},
title = {Straightforward synthesis of novel spiroether derivatives},
journal = {Synthetic Communications},
year = {2021},
publisher = {Taylor & Francis},
month = {apr},
url = {https://www.tandfonline.com/doi/full/10.1080/00397911.2021.1903930},
pages = {1--11},
doi = {10.1080/00397911.2021.1903930}
}