Synthetic Communications, pages 1-11
Straightforward synthesis of novel spiroether derivatives
Publication type: Journal Article
Publication date: 2021-04-07
Journal:
Synthetic Communications
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor: 2.1
ISSN: 00397911, 15322432
Organic Chemistry
Abstract
Abstract We report the first full synthesis of novel spiroether derivatives via reaction of 4-oxobut-2-enoates and alloxan. Our synthesis features the single-step assembly, mild reaction conditions, good yields, high diastereoselectivity, operational simplicity, and the absence of tedious separation procedures. Most of the prepared compounds possessed moderate growth inhibitory effects on human alveolar adenocarcinoma (A549), malignant melanoma (A375), ovarian adenocarcinoma (SK-OV-3), and fibrosarcoma (HT-1080) cell lines. Graphical Abstract
Citations by journals
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4
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Russian Journal of General Chemistry
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Russian Journal of General Chemistry
4 publications, 40%
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Chimica Techno Acta
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Chimica Techno Acta
2 publications, 20%
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Russian Chemical Bulletin
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Russian Chemical Bulletin
2 publications, 20%
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Russian Journal of Organic Chemistry
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Russian Journal of Organic Chemistry
1 publication, 10%
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Drug development & registration
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Drug development & registration
1 publication, 10%
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1
2
3
4
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Citations by publishers
1
2
3
4
5
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Pleiades Publishing
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Pleiades Publishing
5 publications, 50%
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Ural Federal University
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Ural Federal University
2 publications, 20%
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Springer Nature
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Springer Nature
2 publications, 20%
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Center of Pharmaceutical Analytics Ltd
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Center of Pharmaceutical Analytics Ltd
1 publication, 10%
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1
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5
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Bobrovskaya O. V. et al. Straightforward synthesis of novel spiroether derivatives // Synthetic Communications. 2021. pp. 1-11.
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Bobrovskaya O. V., Russkih A. A., Yankin A. N., Dmitriev M. V., Bunev A. S., Gein V. L. Straightforward synthesis of novel spiroether derivatives // Synthetic Communications. 2021. pp. 1-11.
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TY - JOUR
DO - 10.1080/00397911.2021.1903930
UR - https://doi.org/10.1080%2F00397911.2021.1903930
TI - Straightforward synthesis of novel spiroether derivatives
T2 - Synthetic Communications
AU - Bobrovskaya, Olga V
AU - Russkih, Aleksandr A
AU - Yankin, Andrey N
AU - Dmitriev, Maksim V
AU - Bunev, Alexander S.
AU - Gein, V L
PY - 2021
DA - 2021/04/07 00:00:00
PB - Taylor & Francis
SP - 1-11
SN - 0039-7911
SN - 1532-2432
ER -
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@article{2021_Bobrovskaya,
author = {Olga V Bobrovskaya and Aleksandr A Russkih and Andrey N Yankin and Maksim V Dmitriev and Alexander S. Bunev and V L Gein},
title = {Straightforward synthesis of novel spiroether derivatives},
journal = {Synthetic Communications},
year = {2021},
publisher = {Taylor & Francis},
month = {apr},
url = {https://doi.org/10.1080%2F00397911.2021.1903930},
pages = {1--11},
doi = {10.1080/00397911.2021.1903930}
}