Methods and Applications in Fluorescence, volume 7, issue 1, pages 12005
Sensing with photoluminescent semiconductor quantum dots
Publication type: Journal Article
Publication date: 2019-01-24
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor: 3.2
ISSN: 20506120
PubMed ID:
30530939
Spectroscopy
Atomic and Molecular Physics, and Optics
General Materials Science
Instrumentation
Abstract
Fluorescent sensors benefit from high signal-to-noise and multiple measurement modalities, enabling a multitude of applications and flexibility of design. Semiconductor nanocrystal quantum dots (QDs) are excellent fluorophores for sensors because of their extraordinary optical properties. They have high thermal and photochemical stability compared to organic dyes or fluorescent proteins and are extremely bright due to their large molar cross-sections. In contrast to organic dyes, QD emission profiles are symmetric, with relatively narrow bandwidths. In addition, the size tunability of their emission color, which is a result of quantum confinement, make QDs exceptional emitters with high color purity from the ultra-violet to near infrared wavelength range. The role of QDs in sensors ranges from simple fluorescent tags, as used in immunoassays, to intrinsic sensors that utilize the inherent photophysical response of QDs to fluctuations in temperature, electric field, or ion concentration. In more complex configurations, QDs and biomolecular recognition moieties like antibodies are combined with a third component to modulate the optical signal via energy transfer. QDs can act as donors, acceptors, or both in energy transfer-based sensors using Förster resonance energy transfer (FRET), nanometal surface energy transfer (NSET), or charge or electron transfer. The changes in both spectral response and photoluminescent lifetimes have been successfully harnessed to produce sensitive sensors and multiplexed devices. While technical challenges related to biofunctionalization and the high cost of laboratory-grade fluorimeters have thus far prevented broad implementation of QD-based sensing in clinical or commercial settings, improvements in bioconjugation methods and detection schemes, including using simple consumer devices like cell phone cameras, are lowering the barrier to broad use of more sensitive QD-based devices.
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Citations by publishers
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5
10
15
20
25
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Elsevier
22 publications, 26.51%
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American Chemical Society (ACS)
14 publications, 16.87%
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Springer Nature
13 publications, 15.66%
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Royal Society of Chemistry (RSC)
10 publications, 12.05%
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Wiley
7 publications, 8.43%
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Multidisciplinary Digital Publishing Institute (MDPI)
6 publications, 7.23%
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Walter de Gruyter
2 publications, 2.41%
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Pleiades Publishing
1 publication, 1.2%
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Bentham Science
1 publication, 1.2%
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SPIE
1 publication, 1.2%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 1.2%
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5
10
15
20
25
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Chern M. et al. Sensing with photoluminescent semiconductor quantum dots // Methods and Applications in Fluorescence. 2019. Vol. 7. No. 1. p. 12005.
GOST all authors (up to 50)
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Chern M., Kays J. C., Bhuckory S., Dennis A. Sensing with photoluminescent semiconductor quantum dots // Methods and Applications in Fluorescence. 2019. Vol. 7. No. 1. p. 12005.
Cite this
RIS
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TY - JOUR
DO - 10.1088/2050-6120/aaf6f8
UR - https://doi.org/10.1088/2050-6120/aaf6f8
TI - Sensing with photoluminescent semiconductor quantum dots
T2 - Methods and Applications in Fluorescence
AU - Dennis, Allison
AU - Chern, Margaret
AU - Kays, Joshua C
AU - Bhuckory, Shashi
PY - 2019
DA - 2019/01/24 00:00:00
PB - IOP Publishing
SP - 12005
IS - 1
VL - 7
PMID - 30530939
SN - 2050-6120
ER -
Cite this
BibTex
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@article{2019_Chern,
author = {Allison Dennis and Margaret Chern and Joshua C Kays and Shashi Bhuckory},
title = {Sensing with photoluminescent semiconductor quantum dots},
journal = {Methods and Applications in Fluorescence},
year = {2019},
volume = {7},
publisher = {IOP Publishing},
month = {jan},
url = {https://doi.org/10.1088/2050-6120/aaf6f8},
number = {1},
pages = {12005},
doi = {10.1088/2050-6120/aaf6f8}
}
Cite this
MLA
Copy
Chern, Margaret, et al. “Sensing with photoluminescent semiconductor quantum dots.” Methods and Applications in Fluorescence, vol. 7, no. 1, Jan. 2019, p. 12005. https://doi.org/10.1088/2050-6120/aaf6f8.