Open Access
Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction
Publication type: Journal Article
Publication date: 1990-01-01
scimago Q1
wos Q1
SJR: 7.776
CiteScore: 31.7
Impact factor: 13.1
ISSN: 03051048, 13624962
PubMed ID:
2235484
Genetics
Abstract
A hammerhead domain of less than 50 nucleotides is responsible for a self-cleavage reaction in the replication of plant RNA pathogens. The hammerhead is composed of three helices joining at a central conserved core of 11 single stranded nucleotides. The core is believed to fold into a tertiary structure that provides functional groups for catalysis and to coordinate one or more divalent metal ions. In this study we use a phosphorothioate substitution interference assay to identify four phosphates in the conserved core which also play a role in the self-cleavage reaction.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
5
6
|
|
|
Biochemistry
6 publications, 5.22%
|
|
|
Journal of Molecular Biology
6 publications, 5.22%
|
|
|
Nucleic Acids Research
4 publications, 3.48%
|
|
|
Journal of the American Chemical Society
4 publications, 3.48%
|
|
|
Journal of Biological Chemistry
4 publications, 3.48%
|
|
|
Nucleic Acids and Molecular Biology
4 publications, 3.48%
|
|
|
Methods in Enzymology
4 publications, 3.48%
|
|
|
Bioorganic and Medicinal Chemistry Letters
3 publications, 2.61%
|
|
|
Current Opinion in Structural Biology
3 publications, 2.61%
|
|
|
Nature Structural Biology
3 publications, 2.61%
|
|
|
Nucleosides and Nucleotides
3 publications, 2.61%
|
|
|
Science
3 publications, 2.61%
|
|
|
Proceedings of the National Academy of Sciences of the United States of America
3 publications, 2.61%
|
|
|
Annual Review of Biophysics and Biomolecular Structure
3 publications, 2.61%
|
|
|
Annual Review of Biochemistry
3 publications, 2.61%
|
|
|
Bioorganic and Medicinal Chemistry
2 publications, 1.74%
|
|
|
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
2 publications, 1.74%
|
|
|
Antisense and Nucleic Acid Drug Development
2 publications, 1.74%
|
|
|
Nature Structural and Molecular Biology
2 publications, 1.74%
|
|
|
Chemical Communications
2 publications, 1.74%
|
|
|
Journal of Biomolecular Structure and Dynamics
2 publications, 1.74%
|
|
|
Progress in Molecular Biology and Translational Science
2 publications, 1.74%
|
|
|
International Journal of Pharmaceutics
1 publication, 0.87%
|
|
|
Structure
1 publication, 0.87%
|
|
|
Chemistry & Biology
1 publication, 0.87%
|
|
|
Journal of Hepatology
1 publication, 0.87%
|
|
|
Journal of Inorganic Biochemistry
1 publication, 0.87%
|
|
|
Molecular Cell
1 publication, 0.87%
|
|
|
Methods
1 publication, 0.87%
|
|
|
1
2
3
4
5
6
|
Publishers
|
5
10
15
20
25
30
35
40
|
|
|
Elsevier
39 publications, 33.91%
|
|
|
Springer Nature
15 publications, 13.04%
|
|
|
American Chemical Society (ACS)
12 publications, 10.43%
|
|
|
Wiley
7 publications, 6.09%
|
|
|
Taylor & Francis
7 publications, 6.09%
|
|
|
Annual Reviews
7 publications, 6.09%
|
|
|
Oxford University Press
4 publications, 3.48%
|
|
|
American Society for Biochemistry and Molecular Biology
4 publications, 3.48%
|
|
|
American Association for the Advancement of Science (AAAS)
3 publications, 2.61%
|
|
|
Proceedings of the National Academy of Sciences (PNAS)
3 publications, 2.61%
|
|
|
Mary Ann Liebert
2 publications, 1.74%
|
|
|
Royal Society of Chemistry (RSC)
2 publications, 1.74%
|
|
|
Pharmaceutical Society of Japan
1 publication, 0.87%
|
|
|
Pleiades Publishing
1 publication, 0.87%
|
|
|
Cambridge University Press
1 publication, 0.87%
|
|
|
Cold Spring Harbor Laboratory
1 publication, 0.87%
|
|
|
5
10
15
20
25
30
35
40
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
115
Total citations:
115
Citations from 2024:
0
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Ruffner D. E., Uhlenbeck O. C. Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction // Nucleic Acids Research. 1990. Vol. 18. No. 20. pp. 6025-6029.
GOST all authors (up to 50)
Copy
Ruffner D. E., Uhlenbeck O. C. Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction // Nucleic Acids Research. 1990. Vol. 18. No. 20. pp. 6025-6029.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1093/nar/18.20.6025
UR - https://doi.org/10.1093/nar/18.20.6025
TI - Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction
T2 - Nucleic Acids Research
AU - Ruffner, Duane E.
AU - Uhlenbeck, Olke C.
PY - 1990
DA - 1990/01/01
PB - Oxford University Press
SP - 6025-6029
IS - 20
VL - 18
PMID - 2235484
SN - 0305-1048
SN - 1362-4962
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1990_Ruffner,
author = {Duane E. Ruffner and Olke C. Uhlenbeck},
title = {Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction},
journal = {Nucleic Acids Research},
year = {1990},
volume = {18},
publisher = {Oxford University Press},
month = {jan},
url = {https://doi.org/10.1093/nar/18.20.6025},
number = {20},
pages = {6025--6029},
doi = {10.1093/nar/18.20.6025}
}
Cite this
MLA
Copy
Ruffner, Duane E., and Olke C. Uhlenbeck. “Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction.” Nucleic Acids Research, vol. 18, no. 20, Jan. 1990, pp. 6025-6029. https://doi.org/10.1093/nar/18.20.6025.