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Open access
Nucleic Acids Research, volume 40, issue 6, pages 2445-2453

Transcription co-activator SAYP mediates the action of STAT activator

Panov Vladislav V
Kuzmina Julia L
Doronin Semen A
Kopantseva Marina R
Набирочкина Е. Н.
Publication typeJournal Article
Publication date2011-11-28
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor14.9
ISSN03051048, 13624962
PubMed ID:  22123744
Genetics
Abstract
Jak/STAT is an important signaling pathway mediating multiple events in development. We describe participation of metazoan co-activator SAYP/PHF10 in this pathway downstream of STAT. The latter, via its activation domain, interacts with the conserved core of SAYP. STAT is associated with the SAYP-containing co-activator complex BTFly and recruits BTFly onto genes. SAYP is necessary for stimulating STAT-driven transcription of numerous genes. Mutation of SAYP leads to maldevelopments similar to those observed in STAT mutants. Thus, SAYP is a novel co-activator mediating the action of STAT.

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GOST |
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GOST Copy
Panov V. V. et al. Transcription co-activator SAYP mediates the action of STAT activator // Nucleic Acids Research. 2011. Vol. 40. No. 6. pp. 2445-2453.
GOST all authors (up to 50) Copy
Panov V. V., Kuzmina J. L., Doronin S. A., Kopantseva M. R., Набирочкина Е. Н., Георгиева С. Г., Vorobyeva N. E., Shidlovskii Y. V. Transcription co-activator SAYP mediates the action of STAT activator // Nucleic Acids Research. 2011. Vol. 40. No. 6. pp. 2445-2453.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1093/nar/gkr1165
UR - https://doi.org/10.1093%2Fnar%2Fgkr1165
TI - Transcription co-activator SAYP mediates the action of STAT activator
T2 - Nucleic Acids Research
AU - Panov, Vladislav V
AU - Kuzmina, Julia L
AU - Doronin, Semen A
AU - Kopantseva, Marina R
AU - Shidlovskii, Y. V.
AU - Набирочкина, Е. Н.
AU - Георгиева, С. Г.
AU - Vorobyeva, N. E.
PY - 2011
DA - 2011/11/28 00:00:00
PB - Oxford University Press
SP - 2445-2453
IS - 6
VL - 40
PMID - 22123744
SN - 0305-1048
SN - 1362-4962
ER -
BibTex |
Cite this
BibTex Copy
@article{2011_Panov,
author = {Vladislav V Panov and Julia L Kuzmina and Semen A Doronin and Marina R Kopantseva and Y. V. Shidlovskii and Е. Н. Набирочкина and С. Г. Георгиева and N. E. Vorobyeva},
title = {Transcription co-activator SAYP mediates the action of STAT activator},
journal = {Nucleic Acids Research},
year = {2011},
volume = {40},
publisher = {Oxford University Press},
month = {nov},
url = {https://doi.org/10.1093%2Fnar%2Fgkr1165},
number = {6},
pages = {2445--2453},
doi = {10.1093/nar/gkr1165}
}
MLA
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MLA Copy
Panov, Vladislav V., et al. “Transcription co-activator SAYP mediates the action of STAT activator.” Nucleic Acids Research, vol. 40, no. 6, Nov. 2011, pp. 2445-2453. https://doi.org/10.1093%2Fnar%2Fgkr1165.
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