Open Access
Ionic liquids: prospects for nucleic acid handling and delivery
Publication type: Journal Article
Publication date: 2021-01-21
scimago Q1
wos Q1
SJR: 7.776
CiteScore: 31.7
Impact factor: 13.1
ISSN: 03051048, 13624962
PubMed ID:
33476366
Genetics
Abstract
Abstract Operations with nucleic acids are among the main means of studying the mechanisms of gene function and developing novel methods of molecular medicine and gene therapy. These endeavours usually imply the necessity of nucleic acid storage and delivery into eukaryotic cells. In spite of diversity of the existing dedicated techniques, all of them have their limitations. Thus, a recent notion of using ionic liquids in manipulations of nucleic acids has been attracting significant attention lately. Due to their unique physicochemical properties, in particular, their micro-structuring impact and tunability, ionic liquids are currently applied as solvents and stabilizing media in chemical synthesis, electrochemistry, biotechnology, and other areas. Here, we review the current knowledge on interactions between nucleic acids and ionic liquids and discuss potential advantages of applying the latter in delivery of the former into eukaryotic cells.
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Metrics
51
Total citations:
51
Citations from 2024:
23
(45.1%)
Cite this
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RIS |
BibTex |
MLA
Cite this
GOST
Copy
Egorova K. S. et al. Ionic liquids: prospects for nucleic acid handling and delivery // Nucleic Acids Research. 2021. Vol. 49. No. 3. pp. 1201-1234.
GOST all authors (up to 50)
Copy
Egorova K. S., Posvyatenko A. V., Larin S. S., Ananikov V. P. Ionic liquids: prospects for nucleic acid handling and delivery // Nucleic Acids Research. 2021. Vol. 49. No. 3. pp. 1201-1234.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1093/nar/gkaa1280
UR - https://doi.org/10.1093/nar/gkaa1280
TI - Ionic liquids: prospects for nucleic acid handling and delivery
T2 - Nucleic Acids Research
AU - Egorova, Ksenia S
AU - Posvyatenko, Alexandra V
AU - Larin, Sergey S
AU - Ananikov, Valentine P.
PY - 2021
DA - 2021/01/21
PB - Oxford University Press
SP - 1201-1234
IS - 3
VL - 49
PMID - 33476366
SN - 0305-1048
SN - 1362-4962
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Egorova,
author = {Ksenia S Egorova and Alexandra V Posvyatenko and Sergey S Larin and Valentine P. Ananikov},
title = {Ionic liquids: prospects for nucleic acid handling and delivery},
journal = {Nucleic Acids Research},
year = {2021},
volume = {49},
publisher = {Oxford University Press},
month = {jan},
url = {https://doi.org/10.1093/nar/gkaa1280},
number = {3},
pages = {1201--1234},
doi = {10.1093/nar/gkaa1280}
}
Cite this
MLA
Copy
Egorova, Ksenia S., et al. “Ionic liquids: prospects for nucleic acid handling and delivery.” Nucleic Acids Research, vol. 49, no. 3, Jan. 2021, pp. 1201-1234. https://doi.org/10.1093/nar/gkaa1280.
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