Open Access
Transcription co-activator SAYP mediates the action of STAT activator
Publication type: Journal Article
Publication date: 2011-11-28
scimago Q1
wos Q1
SJR: 7.776
CiteScore: 31.7
Impact factor: 13.1
ISSN: 03051048, 13624962
PubMed ID:
22123744
Genetics
Abstract
Jak/STAT is an important signaling pathway mediating multiple events in development. We describe participation of metazoan co-activator SAYP/PHF10 in this pathway downstream of STAT. The latter, via its activation domain, interacts with the conserved core of SAYP. STAT is associated with the SAYP-containing co-activator complex BTFly and recruits BTFly onto genes. SAYP is necessary for stimulating STAT-driven transcription of numerous genes. Mutation of SAYP leads to maldevelopments similar to those observed in STAT mutants. Thus, SAYP is a novel co-activator mediating the action of STAT.
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MLA
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GOST
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Panov V. V. et al. Transcription co-activator SAYP mediates the action of STAT activator // Nucleic Acids Research. 2011. Vol. 40. No. 6. pp. 2445-2453.
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Panov V. V., Kuzmina J. L., Doronin S. A., Kopantseva M. R., Набирочкина Е. Н., Георгиева С. Г., Vorobyeva N. E., Shidlovskii Y. V. Transcription co-activator SAYP mediates the action of STAT activator // Nucleic Acids Research. 2011. Vol. 40. No. 6. pp. 2445-2453.
Cite this
RIS
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TY - JOUR
DO - 10.1093/nar/gkr1165
UR - https://doi.org/10.1093/nar/gkr1165
TI - Transcription co-activator SAYP mediates the action of STAT activator
T2 - Nucleic Acids Research
AU - Panov, Vladislav V
AU - Kuzmina, Julia L
AU - Doronin, Semen A
AU - Kopantseva, Marina R
AU - Набирочкина, Е. Н.
AU - Георгиева, С. Г.
AU - Vorobyeva, N. E.
AU - Shidlovskii, Y. V.
PY - 2011
DA - 2011/11/28
PB - Oxford University Press
SP - 2445-2453
IS - 6
VL - 40
PMID - 22123744
SN - 0305-1048
SN - 1362-4962
ER -
Cite this
BibTex (up to 50 authors)
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@article{2011_Panov,
author = {Vladislav V Panov and Julia L Kuzmina and Semen A Doronin and Marina R Kopantseva and Е. Н. Набирочкина and С. Г. Георгиева and N. E. Vorobyeva and Y. V. Shidlovskii},
title = {Transcription co-activator SAYP mediates the action of STAT activator},
journal = {Nucleic Acids Research},
year = {2011},
volume = {40},
publisher = {Oxford University Press},
month = {nov},
url = {https://doi.org/10.1093/nar/gkr1165},
number = {6},
pages = {2445--2453},
doi = {10.1093/nar/gkr1165}
}
Cite this
MLA
Copy
Panov, Vladislav V., et al. “Transcription co-activator SAYP mediates the action of STAT activator.” Nucleic Acids Research, vol. 40, no. 6, Nov. 2011, pp. 2445-2453. https://doi.org/10.1093/nar/gkr1165.