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Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 12192
Oscillation processes in synuclein-KO mouse skin microcirculation: A pilot study
Kozlov Igor O
1
,
Serov Dmitriy A
2
,
Astashev Maxim E.
2
,
Chaprov K. D.
3
,
Лысикова Е. А.
3
,
Ninkina Natalia
3, 4
,
4
Belgorod National Research Univ. (Russian Federation)
|
Publication type: Proceedings Article
Publication date: 2022-04-29
Quartile SCImago
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ISSN: 16057422
Abstract
The article is devoted to the analysis of skin perfusion oscillation processes with wild-type and synuclein-deficient mice with three knockout (KO) types: αγ-KO, β-KO, and αβγ-KO. The role of synucleins in tissues that exclude the central nervous system remains sparsely studied. Laser Doppler flowmetry was used to investigate the potential involvement of synucleins in murine microcirculation functioning This method is widely used to analyze microcirculatory disturbances in a variety of pathologies and has proven to be sensitive to the manifestation of abnormalities of normal function. The study revealed that deficiency of β-synuclein affects oscillation processes more than αγ-synuclein deficiency.
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Kozlov I. O. et al. Oscillation processes in synuclein-KO mouse skin microcirculation: A pilot study // Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022. Vol. 12192.
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Kozlov I. O., Serov D. A., Seryogina E., Astashev M. E., Tankanag A. V., Chaprov K. D., Лысикова Е. А., Ninkina N., Zherebtsov E. A., Dunaev A. V. Oscillation processes in synuclein-KO mouse skin microcirculation: A pilot study // Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022. Vol. 12192.
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TY - CPAPER
DO - 10.1117/12.2626412
UR - https://doi.org/10.1117%2F12.2626412
TI - Oscillation processes in synuclein-KO mouse skin microcirculation: A pilot study
T2 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
AU - Kozlov, Igor O
AU - Serov, Dmitriy A
AU - Seryogina, Evgeniya
AU - Astashev, Maxim E.
AU - Tankanag, Arina V.
AU - Chaprov, K. D.
AU - Лысикова, Е. А.
AU - Ninkina, Natalia
AU - Zherebtsov, Evgeniy A
AU - Dunaev, Andrey V.
PY - 2022
DA - 2022/04/29 00:00:00
PB - SPIE
VL - 12192
SN - 1605-7422
ER -
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@inproceedings{2022_Kozlov,
author = {Igor O Kozlov and Dmitriy A Serov and Evgeniya Seryogina and Maxim E. Astashev and Arina V. Tankanag and K. D. Chaprov and Е. А. Лысикова and Natalia Ninkina and Evgeniy A Zherebtsov and Andrey V. Dunaev},
title = {Oscillation processes in synuclein-KO mouse skin microcirculation: A pilot study},
year = {2022},
volume = {12192},
month = {apr},
publisher = {SPIE}
}