Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent
Michael F Kuhrt
1
,
Marilyn J Fancher
1
,
Venkatanarayana Jasty
1
,
Francis Pancic
1
,
Paul E Came
1
1
Department of Microbiology, Sterling-Winthrop Research Institute, Rensselaer, New York 12144
|
Publication type: Journal Article
Publication date: 1979-06-09
scimago Q1
wos Q1
SJR: 1.431
CiteScore: 8.4
Impact factor: 4.5
ISSN: 00664804, 10986596
PubMed ID:
224808
Pharmacology
Infectious Diseases
Pharmacology (medical)
Abstract
Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be partially reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone.
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Total citations:
19
Citations from 2024:
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GOST
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Kuhrt M. F. et al. Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent // Antimicrobial Agents and Chemotherapy. 1979. Vol. 15. No. 6. pp. 813-819.
GOST all authors (up to 50)
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Kuhrt M. F., Fancher M. J., Jasty V., Pancic F., Came P. E. Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent // Antimicrobial Agents and Chemotherapy. 1979. Vol. 15. No. 6. pp. 813-819.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1128/aac.15.6.813
UR - https://doi.org/10.1128/aac.15.6.813
TI - Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent
T2 - Antimicrobial Agents and Chemotherapy
AU - Kuhrt, Michael F
AU - Fancher, Marilyn J
AU - Jasty, Venkatanarayana
AU - Pancic, Francis
AU - Came, Paul E
PY - 1979
DA - 1979/06/09
PB - American Society for Microbiology
SP - 813-819
IS - 6
VL - 15
PMID - 224808
SN - 0066-4804
SN - 1098-6596
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1979_Kuhrt,
author = {Michael F Kuhrt and Marilyn J Fancher and Venkatanarayana Jasty and Francis Pancic and Paul E Came},
title = {Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent},
journal = {Antimicrobial Agents and Chemotherapy},
year = {1979},
volume = {15},
publisher = {American Society for Microbiology},
month = {jun},
url = {https://doi.org/10.1128/aac.15.6.813},
number = {6},
pages = {813--819},
doi = {10.1128/aac.15.6.813}
}
Cite this
MLA
Copy
Kuhrt, Michael F., et al. “Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent.” Antimicrobial Agents and Chemotherapy, vol. 15, no. 6, Jun. 1979, pp. 813-819. https://doi.org/10.1128/aac.15.6.813.