A Global Perspective on Hantavirus Ecology, Epidemiology, and Disease
SUMMARY
Hantaviruses are enzootic viruses that maintain persistent infections in their rodent hosts without apparent disease symptoms. The spillover of these viruses to humans can lead to one of two serious illnesses, hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome. In recent years, there has been an improved understanding of the epidemiology, pathogenesis, and natural history of these viruses following an increase in the number of outbreaks in the Americas. In this review, current concepts regarding the ecology of and disease associated with these serious human pathogens are presented. Priorities for future research suggest an integration of the ecology and evolution of these and other host-virus ecosystems through modeling and hypothesis-driven research with the risk of emergence, host switching/spillover, and disease transmission to humans.
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PLoS ONE
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Emerging Infectious Diseases
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Journal of Medical Virology
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Frontiers in Cellular and Infection Microbiology
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Scientific Reports
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Virus Research
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Journal of General Virology
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Frontiers in Microbiology
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BMC Infectious Diseases
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Virology Journal
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Infection, Genetics and Evolution
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Vector-Borne and Zoonotic Diseases
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Frontiers in Immunology
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Epidemiology and Infection
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Elsevier
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Springer Nature
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MDPI
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Public Library of Science (PLoS)
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Wiley
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Frontiers Media S.A.
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American Society for Microbiology
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Cold Spring Harbor Laboratory
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Taylor & Francis
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Oxford University Press
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Centers for Disease Control and Prevention (CDC)
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Microbiology Society
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Mary Ann Liebert
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Cambridge University Press
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Ovid Technologies (Wolters Kluwer Health)
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eLife Sciences Publications
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Proceedings of the National Academy of Sciences (PNAS)
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