том 85 издание 4 страницы 425-435

Translesion DNA Synthesis and Carcinogenesis

Тип публикацииJournal Article
Дата публикации2020-04-27
SCImago Q2
WOS Q4
БС2
SJR0.609
CiteScore3.8
Impact factor2.2
ISSN00062979, 16083040
Biochemistry
General Medicine
Biophysics
Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Краткое описание
Tens of thousands of DNA lesions are formed in mammalian cells each day. DNA translesion synthesis is the main mechanism of cell defense against unrepaired DNA lesions. DNA polymerases iota (Pol ι), eta (Pol η), kappa (Pol κ), and zeta (Pol ζ) have active sites that are less stringent toward the DNA template structure and efficiently incorporate nucleotides opposite DNA lesions. However, these polymerases display low accuracy of DNA synthesis and can introduce mutations in genomic DNA. Impaired functioning of these enzymes can lead to an increased risk of cancer.
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ГОСТ |
Цитировать
Shilkin E. S. et al. Translesion DNA Synthesis and Carcinogenesis // Biochemistry (Moscow). 2020. Vol. 85. No. 4. pp. 425-435.
ГОСТ со всеми авторами (до 50) Скопировать
Shilkin E. S., Boldinova E. O., Stolyarenko A. D., Goncharova R. I., Chuprov-Netochin R. N., Khairullin R. F., Smal M. P., Makarova A. V. Translesion DNA Synthesis and Carcinogenesis // Biochemistry (Moscow). 2020. Vol. 85. No. 4. pp. 425-435.
RIS |
Цитировать
TY - JOUR
DO - 10.1134/s0006297920040033
UR - https://doi.org/10.1134/s0006297920040033
TI - Translesion DNA Synthesis and Carcinogenesis
T2 - Biochemistry (Moscow)
AU - Shilkin, E S
AU - Boldinova, E O
AU - Stolyarenko, A D
AU - Goncharova, R. I.
AU - Chuprov-Netochin, R. N.
AU - Khairullin, R F
AU - Smal, M P
AU - Makarova, A. V.
PY - 2020
DA - 2020/04/27
PB - Pleiades Publishing
SP - 425-435
IS - 4
VL - 85
PMID - 32569550
SN - 0006-2979
SN - 1608-3040
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2020_Shilkin,
author = {E S Shilkin and E O Boldinova and A D Stolyarenko and R. I. Goncharova and R. N. Chuprov-Netochin and R F Khairullin and M P Smal and A. V. Makarova},
title = {Translesion DNA Synthesis and Carcinogenesis},
journal = {Biochemistry (Moscow)},
year = {2020},
volume = {85},
publisher = {Pleiades Publishing},
month = {apr},
url = {https://doi.org/10.1134/s0006297920040033},
number = {4},
pages = {425--435},
doi = {10.1134/s0006297920040033}
}
MLA
Цитировать
Shilkin, E. S., et al. “Translesion DNA Synthesis and Carcinogenesis.” Biochemistry (Moscow), vol. 85, no. 4, Apr. 2020, pp. 425-435. https://doi.org/10.1134/s0006297920040033.
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