Pleiades Publishing
Radiochemistry
,  volume 65 ,  issue 6 ,  pages 690-698

Tritium Labeling Vancomycin and Studying Its Adsorption on Nanodiamonds

Publication type: Journal Article
Publication date: 2023-12-01
Pleiades Publishing
scimago Q3
wos Q4
SJR: 0.285
CiteScore: 1.6
Impact factor: 1.0
ISSN: 10663622, 16083288
Physical and Theoretical Chemistry
Abstract
Procedure of tritium labeling vancomycin synthesis using tritium thermal activation method was developed. The influence of target mass on the specific and total radioactivity was revealed. [3H]Vancomycin was used for studying its equilibrium adsorption on nanodiamonds as well as its amount that tightly bonded to surface and did not remove with water. It was found that vancomycin is adsorbed from aqueous solution via strong bonding to nanodiamonds and is not washed out with water. Application of 0.028 M phosphate buffer (pH 6.7 and 2.7) increased the equilibrium vancomycin adsorption about one and a half times, while vancomycin amount in the adsorption complex with nanodiamonds after washing with water was significantly reduced. Such behavior of vancomycin is due to the presence of phosphate-ions that contribute to vancomycin adsorption but are washed out with water. Molecular mechanics simulation allows the suggestion that the formation of multiple hydrogen bonds is required for generation of a durable adsorption complex of vancomycin with nanodiamonds.
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GOST |
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GOST Copy
Shen Т. et al. Tritium Labeling Vancomycin and Studying Its Adsorption on Nanodiamonds // Radiochemistry. 2023. Vol. 65. No. 6. pp. 690-698.
GOST all authors (up to 50) Copy
Shen Т., Chernysheva M. G., Badun G. Tritium Labeling Vancomycin and Studying Its Adsorption on Nanodiamonds // Radiochemistry. 2023. Vol. 65. No. 6. pp. 690-698.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/s1066362223060103
UR - https://link.springer.com/10.1134/S1066362223060103
TI - Tritium Labeling Vancomycin and Studying Its Adsorption on Nanodiamonds
T2 - Radiochemistry
AU - Shen, Т.
AU - Chernysheva, M G
AU - Badun, G.A.
PY - 2023
DA - 2023/12/01
PB - Pleiades Publishing
SP - 690-698
IS - 6
VL - 65
SN - 1066-3622
SN - 1608-3288
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Shen,
author = {Т. Shen and M G Chernysheva and G.A. Badun},
title = {Tritium Labeling Vancomycin and Studying Its Adsorption on Nanodiamonds},
journal = {Radiochemistry},
year = {2023},
volume = {65},
publisher = {Pleiades Publishing},
month = {dec},
url = {https://link.springer.com/10.1134/S1066362223060103},
number = {6},
pages = {690--698},
doi = {10.1134/s1066362223060103}
}
MLA
Cite this
MLA Copy
Shen, Т., et al. “Tritium Labeling Vancomycin and Studying Its Adsorption on Nanodiamonds.” Radiochemistry, vol. 65, no. 6, Dec. 2023, pp. 690-698. https://link.springer.com/10.1134/S1066362223060103.