Inorganic Materials: Applied Research

, volume 13 , issue 4 , pages 952-960

Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP

Yu S Lukina ^{1, 2}

B P Mishchenko ³

V V Zaytsev ²

M. G. Vasil'ev ²

I I Selezneva ⁴

Hide authors affiliations Show authors affiliations: 4 affiliations

Mendeleev University of Chemical Technology of Russia (MUCTR), Moscow, Russia |

National Medical Research Center for Traumatology and Orthopedics named after N.N. Priorov, Ministry of Health of the Russian Federation, Moscow, Russia |

LLC COMPANY ELTA, Moscow, Russia |

⁴

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia |

Publication type: Journal Article

Publication date: 2022-07-19

Pleiades Publishing

Inorganic Materials: Applied Research

scimago Q4

wos Q4

SJR: 0.162

CiteScore: 0.8

Impact factor: 0.3

ISSN: 20751133, 2075115X

DOI: 10.1134/s2075113322040244

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General Materials Science

General Engineering

Abstract

A technology has been developed for obtaining and evaluating in model studies in vitro a chemically fixed xenogenic bone matrix structurally resistant to osteoclastic resorption. The parameters of demineralization of the fragmented bone matrix have been selected in which the complete removal of the mineral component is carried out with the preservation of collagen in its native state. Optimal technological parameters of chemical fixation with epoxy compounds make it possible to obtain a stable material with free epoxy groups which can serve as a carrier for recombinant protein growth factors (rhBMP) in conditions of a pronounced regenerative process.

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Lukina Yu. S. et al. Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP // Inorganic Materials: Applied Research. 2022. Vol. 13. No. 4. pp. 952-960.

GOST all authors (up to 50) Copy

Lukina Yu. S., Mishchenko B. P., Zaytsev V. V., Vasil'ev M. G., Selezneva I. I. Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP // Inorganic Materials: Applied Research. 2022. Vol. 13. No. 4. pp. 952-960.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1134/s2075113322040244

UR - https://link.springer.com/10.1134/S2075113322040244

TI - Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP

T2 - Inorganic Materials: Applied Research

AU - Lukina, Yu S

AU - Mishchenko, B P

AU - Zaytsev, V V

AU - Vasil'ev, M. G.

AU - Selezneva, I I

PY - 2022

DA - 2022/07/19

PB - Pleiades Publishing

SP - 952-960

IS - 4

VL - 13

SN - 2075-1133

SN - 2075-115X

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2022_Lukina,

author = {Yu S Lukina and B P Mishchenko and V V Zaytsev and M. G. Vasil'ev and I I Selezneva},

title = {Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP},

journal = {Inorganic Materials: Applied Research},

year = {2022},

volume = {13},

publisher = {Pleiades Publishing},

month = {jul},

url = {https://link.springer.com/10.1134/S2075113322040244},

number = {4},

pages = {952--960},

doi = {10.1134/s2075113322040244}

}

MLA

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MLA Copy

Lukina, Yu. S., et al. “Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP.” Inorganic Materials: Applied Research, vol. 13, no. 4, Jul. 2022, pp. 952-960. https://link.springer.com/10.1134/S2075113322040244.