Molecular Biology, volume 40, issue 5, pages 675-687
Structural changes in the ribosome during the elongation cycle
Publication type: Journal Article
Publication date: 2006-10-10
Journal:
Molecular Biology
Quartile SCImago
Q4
Quartile WOS
Q4
Impact factor: 1.2
ISSN: 00268933, 16083245
Structural Biology
Biophysics
Abstract
Ample data on structural changes that arise in the ribosome during translation have been accumulated. The most interesting information on such changes has been obtained by cryoelectron microscopy of ribosome complexes with various ligands and by rRNA site-directed mutagenesis combined with a structural analysis of the ribosome by a chemical modification technique (chemical probing). The review considers the best-known structural changes that arise in the translating ribosome upon its interactions with tRNA and the elongation factors. The changes are discussed in the context of interactions between the functional centers of the ribosome. A universal system of rRNA helices and proteins is described in detail. The system integrates the functional centers of the ribosome and allows transduction of allosteric conformational signals. Biochemical data are considered in terms of the structures and interactions of ribosomal elements, and a hypothesis is advanced that the position of the GTPase-associated center in the ribosome regulates the binding of the elongation factors.
Citations by journals
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2
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Biochemistry (Moscow)
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Biochemistry (Moscow)
2 publications, 40%
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Molecular Biology
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Molecular Biology
1 publication, 20%
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Nucleic Acids Research
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Nucleic Acids Research
1 publication, 20%
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1
2
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Citations by publishers
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1
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3
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Pleiades Publishing
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Pleiades Publishing
3 publications, 60%
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Oxford University Press
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Oxford University Press
1 publication, 20%
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1
2
3
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Kiparisov S. V. et al. Structural changes in the ribosome during the elongation cycle // Molecular Biology. 2006. Vol. 40. No. 5. pp. 675-687.
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Kiparisov S. V., Sergiev P. V., Bogdanov A. A., Dontsova O. A. Structural changes in the ribosome during the elongation cycle // Molecular Biology. 2006. Vol. 40. No. 5. pp. 675-687.
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TY - JOUR
DO - 10.1134/S0026893306050013
UR - https://doi.org/10.1134%2FS0026893306050013
TI - Structural changes in the ribosome during the elongation cycle
T2 - Molecular Biology
AU - Kiparisov, S V
AU - Sergiev, P V
AU - Bogdanov, A. A.
AU - Dontsova, O. A.
PY - 2006
DA - 2006/10/10 00:00:00
PB - Pleiades Publishing
SP - 675-687
IS - 5
VL - 40
SN - 0026-8933
SN - 1608-3245
ER -
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@article{2006_Kiparisov,
author = {S V Kiparisov and P V Sergiev and A. A. Bogdanov and O. A. Dontsova},
title = {Structural changes in the ribosome during the elongation cycle},
journal = {Molecular Biology},
year = {2006},
volume = {40},
publisher = {Pleiades Publishing},
month = {oct},
url = {https://doi.org/10.1134%2FS0026893306050013},
number = {5},
pages = {675--687},
doi = {10.1134/S0026893306050013}
}
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MLA
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Kiparisov, S. V., et al. “Structural changes in the ribosome during the elongation cycle.” Molecular Biology, vol. 40, no. 5, Oct. 2006, pp. 675-687. https://doi.org/10.1134%2FS0026893306050013.
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