Selective Radiosensitizing Effect of Amorphous Hafnia Modified with Organic Quantum Dots on Normal and Malignant Cells
N. P. Popova
1, 2
,
G S Taran
1
,
A.L. Popov
1, 2
,
D.D. Kolmanovich
2
,
A E Baranchikov
1
,
S.S. Sorokina
2
,
K Yu Zhizhin
1
,
Publication type: Journal Article
Publication date: 2021-06-29
scimago Q3
wos Q4
SJR: 0.270
CiteScore: 3.0
Impact factor: 1.5
ISSN: 00360236, 15318613
Inorganic Chemistry
Physical and Theoretical Chemistry
Materials Science (miscellaneous)
Abstract
Abstract —Aqueous sols of hafnia modified with organic quantum dots, which exhibit pronounced luminescent properties, have been synthesized by hydrothermal treatment of amorphous hydrated hafnium dioxide in the presence of ammonium citrate. It has been shown that malignant human cells of the U-251, MCF-7, and MNNG/Hos lines take up the resulting nanoparticles to a significantly higher degree than human mesenchymal stem cells. Under X-ray radiation (15 Gy), the resulting nanoparticles exhibit radiosensitizing properties against malignant cells of the U-251 and MCF-7 lines, significantly reducing their viability. On the contrary, in relation to human osteosarcoma cells of the MNNG/Hos line, the radiosensitizing properties of the obtained material are much less pronounced.
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Popova N. P. et al. Selective Radiosensitizing Effect of Amorphous Hafnia Modified with Organic Quantum Dots on Normal and Malignant Cells // Russian Journal of Inorganic Chemistry. 2021. Vol. 66. No. 6. pp. 931-937.
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Popova N. P., Taran G. S., Popov A., Kolmanovich D., Baranchikov A. E., Sorokina S., Zhizhin K. Yu., Ivanov V. Selective Radiosensitizing Effect of Amorphous Hafnia Modified with Organic Quantum Dots on Normal and Malignant Cells // Russian Journal of Inorganic Chemistry. 2021. Vol. 66. No. 6. pp. 931-937.
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TY - JOUR
DO - 10.1134/S0036023621060164
UR - https://link.springer.com/10.1134/S0036023621060164
TI - Selective Radiosensitizing Effect of Amorphous Hafnia Modified with Organic Quantum Dots on Normal and Malignant Cells
T2 - Russian Journal of Inorganic Chemistry
AU - Popova, N. P.
AU - Taran, G S
AU - Popov, A.L.
AU - Kolmanovich, D.D.
AU - Baranchikov, A E
AU - Sorokina, S.S.
AU - Zhizhin, K Yu
AU - Ivanov, V.K.
PY - 2021
DA - 2021/06/29
PB - Pleiades Publishing
SP - 931-937
IS - 6
VL - 66
SN - 0036-0236
SN - 1531-8613
ER -
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@article{2021_Popova,
author = {N. P. Popova and G S Taran and A.L. Popov and D.D. Kolmanovich and A E Baranchikov and S.S. Sorokina and K Yu Zhizhin and V.K. Ivanov},
title = {Selective Radiosensitizing Effect of Amorphous Hafnia Modified with Organic Quantum Dots on Normal and Malignant Cells},
journal = {Russian Journal of Inorganic Chemistry},
year = {2021},
volume = {66},
publisher = {Pleiades Publishing},
month = {jun},
url = {https://link.springer.com/10.1134/S0036023621060164},
number = {6},
pages = {931--937},
doi = {10.1134/S0036023621060164}
}
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MLA
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Popova, N. P., et al. “Selective Radiosensitizing Effect of Amorphous Hafnia Modified with Organic Quantum Dots on Normal and Malignant Cells.” Russian Journal of Inorganic Chemistry, vol. 66, no. 6, Jun. 2021, pp. 931-937. https://link.springer.com/10.1134/S0036023621060164.