Pleiades Publishing
Polymer Science - Series A
,  volume 61 ,  issue 3 ,  pages 296-307

Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances

V V Spiridonov 1
, 
I. G. Panova 1
, 
A V Sybachin 1
, 
V. V. Kuznetsov 1
, 
M.I Afanasov 1
, 
Yu A Alekhina 2
, 
N.S. Melik-Nubarov 1
, 
A A Yaroslavov 1
1
 
2
 
Publication type: Journal Article
Publication date: 2019-05-31
Pleiades Publishing
scimago Q3
wos Q4
SJR: 0.244
CiteScore: 1.9
Impact factor: 1.1
ISSN: 0965545X, 15556107, 17571820
Materials Chemistry
Polymers and Plastics
Abstract
Multiliposomal containers obtained by the successive adsorption of cationic polypeptide poly(L-lysine) and anionic liposomes on the surface of anionic magnetic microgels—the products of γ-Fe2O3 (maghemite) synthesis in the matrix of natural anionic polysaccharide—the mixed Na/Ca salt of alginic acid—are presented. The composition and morphology of magneto-sensitive microgels are studied by X-ray analysis, FTIR spectroscopy, Mössbauer spectroscopy, magnetometry, and transmission electron microscopy. The size of particles of multiliposomal containers with the ultimate liposome content in the physiological solution is about 400 nm. They are not cytotoxic up to a poly(L-lysine) concentration of 600 μM. It is shown that these objects filled with antitumor antibiotic—doxorubicin—are able to move in a suspension under application of an external magnetic field with the integrity of liposomes in the container being preserved. The obtained containers are promising for the controlled delivery of bioactive substances (drugs).
Found 
Found 

Top-30

Journals

1
Expert Opinion on Drug Delivery
Expert Opinion on Drug Delivery, 1, 33.33%
Expert Opinion on Drug Delivery
1 publication, 33.33%
Polymer Science - Series C
Polymer Science - Series C, 1, 33.33%
Polymer Science - Series C
1 publication, 33.33%
Высокомолекулярные соединения С
Высокомолекулярные соединения С, 1, 33.33%
Высокомолекулярные соединения С
1 publication, 33.33%
1

Publishers

1
Taylor & Francis
Taylor & Francis, 1, 33.33%
Taylor & Francis
1 publication, 33.33%
Pleiades Publishing
Pleiades Publishing, 1, 33.33%
Pleiades Publishing
1 publication, 33.33%
The Russian Academy of Sciences
The Russian Academy of Sciences, 1, 33.33%
The Russian Academy of Sciences
1 publication, 33.33%
1
  • We do not take into account publications without a DOI.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
3
Share
Cite this
GOST |
Cite this
GOST Copy
Spiridonov V. V. et al. Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances // Polymer Science - Series A. 2019. Vol. 61. No. 3. pp. 296-307.
GOST all authors (up to 50) Copy
Spiridonov V. V., Panova I. G., Sybachin A. V., Kuznetsov V. V., Afanasov M., Alekhina Yu. A., Melik-Nubarov N., Yaroslavov A. A. Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances // Polymer Science - Series A. 2019. Vol. 61. No. 3. pp. 296-307.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/S0965545X19030167
UR - http://link.springer.com/10.1134/S0965545X19030167
TI - Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances
T2 - Polymer Science - Series A
AU - Spiridonov, V V
AU - Panova, I. G.
AU - Sybachin, A V
AU - Kuznetsov, V. V.
AU - Afanasov, M.I
AU - Alekhina, Yu A
AU - Melik-Nubarov, N.S.
AU - Yaroslavov, A A
PY - 2019
DA - 2019/05/31
PB - Pleiades Publishing
SP - 296-307
IS - 3
VL - 61
SN - 0965-545X
SN - 1555-6107
SN - 1757-1820
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Spiridonov,
author = {V V Spiridonov and I. G. Panova and A V Sybachin and V. V. Kuznetsov and M.I Afanasov and Yu A Alekhina and N.S. Melik-Nubarov and A A Yaroslavov},
title = {Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances},
journal = {Polymer Science - Series A},
year = {2019},
volume = {61},
publisher = {Pleiades Publishing},
month = {may},
url = {http://link.springer.com/10.1134/S0965545X19030167},
number = {3},
pages = {296--307},
doi = {10.1134/S0965545X19030167}
}
MLA
Cite this
MLA Copy
Spiridonov, V. V., et al. “Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances.” Polymer Science - Series A, vol. 61, no. 3, May. 2019, pp. 296-307. http://link.springer.com/10.1134/S0965545X19030167.