volume 71 issue 14 pages 1326-1331

Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry

A P Topolyan 1
D A Strizhevskaya 1
M S Slyundina 2, 3
M A Belyaeva 1
O. M. Ivanova 1
V A Korshun 1, 2
A. V. Ustinov 1
I V Mikhura 1
A.A Formanovsky 1
Publication typeJournal Article
Publication date2016-12-01
scimago Q3
wos Q4
SJR0.252
CiteScore1.9
Impact factor1.1
ISSN10619348, 16083199
Analytical Chemistry
Abstract
A novel derivatization method for the analysis of primary amines by MALDI mass spectrometry is proposed. Tris(2,6-dimethoxyphenyl) methyl carbenium cation reacts smoothly with primary amines, forming permanently charged adducts with the mass increment +359 Da and absorbance in the UV region. The approach was tested on a number of amines, including biologically active compounds and therapeutic agents.
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Topolyan A. P. et al. Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry // Journal of Analytical Chemistry. 2016. Vol. 71. No. 14. pp. 1326-1331.
GOST all authors (up to 50) Copy
Topolyan A. P., Strizhevskaya D. A., Slyundina M. S., Belyaeva M. A., Ivanova O. M., Korshun V. A., Ustinov A. V., Mikhura I. V., Formanovsky A., Borisov R. S. Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry // Journal of Analytical Chemistry. 2016. Vol. 71. No. 14. pp. 1326-1331.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/S106193481614015X
UR - https://doi.org/10.1134/S106193481614015X
TI - Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry
T2 - Journal of Analytical Chemistry
AU - Topolyan, A P
AU - Strizhevskaya, D A
AU - Slyundina, M S
AU - Belyaeva, M A
AU - Ivanova, O. M.
AU - Korshun, V A
AU - Ustinov, A. V.
AU - Mikhura, I V
AU - Formanovsky, A.A
AU - Borisov, R S
PY - 2016
DA - 2016/12/01
PB - Pleiades Publishing
SP - 1326-1331
IS - 14
VL - 71
SN - 1061-9348
SN - 1608-3199
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Topolyan,
author = {A P Topolyan and D A Strizhevskaya and M S Slyundina and M A Belyaeva and O. M. Ivanova and V A Korshun and A. V. Ustinov and I V Mikhura and A.A Formanovsky and R S Borisov},
title = {Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry},
journal = {Journal of Analytical Chemistry},
year = {2016},
volume = {71},
publisher = {Pleiades Publishing},
month = {dec},
url = {https://doi.org/10.1134/S106193481614015X},
number = {14},
pages = {1326--1331},
doi = {10.1134/S106193481614015X}
}
MLA
Cite this
MLA Copy
Topolyan, A. P., et al. “Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry.” Journal of Analytical Chemistry, vol. 71, no. 14, Dec. 2016, pp. 1326-1331. https://doi.org/10.1134/S106193481614015X.