Shape Determination of Bovine Fibrinogen in Solution Using Small-Angle Scattering Data
1
4
Publication type: Journal Article
Publication date: 2018-11-01
scimago Q4
wos Q4
SJR: 0.145
CiteScore: 0.8
Impact factor: 0.5
ISSN: 10637745, 1562689X
General Chemistry
Condensed Matter Physics
General Materials Science
Abstract
A 3D model of the shape of bovine fibrinogen, one of the proteins responsible for blood coagulation, is constructed based on small-angle X-ray scattering (SAXS) data on bovine fibrinogen in solution, and the oligomeric composition of fibrinogen in solution is estimated. It is shown that fibrinogen molecules form elongated vermicular structures with a length on the order of 50 nm and an effective cross section of about 10 nm. The volume of these particles correlates well with the volume of two fibrinogen dimers. The results obtained may be helpful when applying fibrinogen and its modifications in tissue engineering.
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Kryukova A. E. et al. Shape Determination of Bovine Fibrinogen in Solution Using Small-Angle Scattering Data // Crystallography Reports. 2018. Vol. 63. No. 6. pp. 871-873.
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Kryukova A. E., Shpichka A. I., Konarev P., Volkov V. V., Timashev P. S., Asadchikov V. E. Shape Determination of Bovine Fibrinogen in Solution Using Small-Angle Scattering Data // Crystallography Reports. 2018. Vol. 63. No. 6. pp. 871-873.
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RIS
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TY - JOUR
DO - 10.1134/S1063774518060202
UR - https://doi.org/10.1134/S1063774518060202
TI - Shape Determination of Bovine Fibrinogen in Solution Using Small-Angle Scattering Data
T2 - Crystallography Reports
AU - Kryukova, A E
AU - Shpichka, A I
AU - Konarev, P.V.
AU - Volkov, V. V.
AU - Timashev, P S
AU - Asadchikov, V. E.
PY - 2018
DA - 2018/11/01
PB - Pleiades Publishing
SP - 871-873
IS - 6
VL - 63
SN - 1063-7745
SN - 1562-689X
ER -
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BibTex (up to 50 authors)
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@article{2018_Kryukova,
author = {A E Kryukova and A I Shpichka and P.V. Konarev and V. V. Volkov and P S Timashev and V. E. Asadchikov},
title = {Shape Determination of Bovine Fibrinogen in Solution Using Small-Angle Scattering Data},
journal = {Crystallography Reports},
year = {2018},
volume = {63},
publisher = {Pleiades Publishing},
month = {nov},
url = {https://doi.org/10.1134/S1063774518060202},
number = {6},
pages = {871--873},
doi = {10.1134/S1063774518060202}
}
Cite this
MLA
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Kryukova, A. E., et al. “Shape Determination of Bovine Fibrinogen in Solution Using Small-Angle Scattering Data.” Crystallography Reports, vol. 63, no. 6, Nov. 2018, pp. 871-873. https://doi.org/10.1134/S1063774518060202.