Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid
Publication type: Journal Article
Publication date: 2018-09-01
scimago Q4
wos Q3
SJR: 0.267
CiteScore: 1.9
Impact factor: 1.7
ISSN: 10681620, 1608330X, 15739163
Organic Chemistry
Biochemistry
Abstract
An effective method of a modification of the anhydride ring of the maleopimaric acid methyl ester by means of the cyanoethylation reaction was developed. A primary screening of a cytotoxic activity in vitro demonstrated an ability of the cyanoethyl derivative of the maleopimaric acid methyl ester to induce the death of the PC-3 cells of prostate cancer.
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Tretyakova E. V., Salimova E. V., Parfenova L. V. Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid // Russian Journal of Bioorganic Chemistry. 2018. Vol. 44. No. 5. pp. 547-552.
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Tretyakova E. V., Salimova E. V., Parfenova L. V. Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid // Russian Journal of Bioorganic Chemistry. 2018. Vol. 44. No. 5. pp. 547-552.
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RIS
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TY - JOUR
DO - 10.1134/S1068162018050175
UR - https://doi.org/10.1134/S1068162018050175
TI - Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid
T2 - Russian Journal of Bioorganic Chemistry
AU - Tretyakova, E V
AU - Salimova, E V
AU - Parfenova, L V
PY - 2018
DA - 2018/09/01
PB - Pleiades Publishing
SP - 547-552
IS - 5
VL - 44
SN - 1068-1620
SN - 1608-330X
SN - 1573-9163
ER -
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BibTex (up to 50 authors)
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@article{2018_Tretyakova,
author = {E V Tretyakova and E V Salimova and L V Parfenova},
title = {Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid},
journal = {Russian Journal of Bioorganic Chemistry},
year = {2018},
volume = {44},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/S1068162018050175},
number = {5},
pages = {547--552},
doi = {10.1134/S1068162018050175}
}
Cite this
MLA
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Tretyakova, E. V., et al. “Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid.” Russian Journal of Bioorganic Chemistry, vol. 44, no. 5, Sep. 2018, pp. 547-552. https://doi.org/10.1134/S1068162018050175.
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