Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation
Тип публикации: Journal Article
Дата публикации: 2019-10-01
scimago Q4
wos Q4
БС2
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Краткое описание
Glutathione-capped gold nanoclusters display polyanionic properties that are manifested in the interaction with cationic species. The nanoclusters form complexes with doxorubicin with effective dissociation constant about 10 µM that increased by an order of magnitude in the presence of 0.15 M NaCl confirming electrostatic character of binding. Adsorption of polylysine arose an increase in the fluorescence of gold nanoclusters due to aggregation induced emission enhancement effect. Fluorescence of the complexes increased several-fold upon addition of up to 1 M of KCl suggesting contribution of non-Coulombic forces in the stabilization of aggregates of gold nanoclusters.
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Iakimov N. P. et al. Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation // Russian Journal of General Chemistry. 2019. Vol. 89. No. 10. pp. 2097-2102.
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Iakimov N. P., Abdullina V. R., Sharanov P. A., Alov N. V., Orlov V. N., Grozdova I. D., Melik-Nubarov N. Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation // Russian Journal of General Chemistry. 2019. Vol. 89. No. 10. pp. 2097-2102.
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TY - JOUR
DO - 10.1134/S1070363219100177
UR - http://link.springer.com/10.1134/S1070363219100177
TI - Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation
T2 - Russian Journal of General Chemistry
AU - Iakimov, N P
AU - Abdullina, Va R
AU - Sharanov, P A
AU - Alov, N V
AU - Orlov, V. N.
AU - Grozdova, I D
AU - Melik-Nubarov, N.S.
PY - 2019
DA - 2019/10/01
PB - Pleiades Publishing
SP - 2097-2102
IS - 10
VL - 89
SN - 1070-3632
SN - 1608-3350
ER -
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@article{2019_Iakimov,
author = {N P Iakimov and Va R Abdullina and P A Sharanov and N V Alov and V. N. Orlov and I D Grozdova and N.S. Melik-Nubarov},
title = {Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation},
journal = {Russian Journal of General Chemistry},
year = {2019},
volume = {89},
publisher = {Pleiades Publishing},
month = {oct},
url = {http://link.springer.com/10.1134/S1070363219100177},
number = {10},
pages = {2097--2102},
doi = {10.1134/S1070363219100177}
}
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MLA
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Iakimov, N. P., et al. “Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation.” Russian Journal of General Chemistry, vol. 89, no. 10, Oct. 2019, pp. 2097-2102. http://link.springer.com/10.1134/S1070363219100177.