Doklady Biochemistry and Biophysics, volume 464, issue 1, pages 329-332
DNA methylation of genes of the main components of the telomerase complex in Danio rerio
Belova E. V.
1
,
Kozlov A E
1
,
Shubernetskaya O S
1
,
Zvereva M I
1
,
Shpanchenko O V
1
,
Dontsova O. A.
1, 2
Publication type: Journal Article
Publication date: 2015-09-01
Journal:
Doklady Biochemistry and Biophysics
Quartile SCImago
Q3
Quartile WOS
Q4
Impact factor: 0.8
ISSN: 16076729, 16083091
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract
The methylation status of the genes of telomerase reverse transcriptase (tert) and telomerase RNA (terc) was determined in brain tissues of Danio rerio of different age. It is found that, regardless of the age of fish, the regulatory region of the tert gene was completely methylated, whereas the coding region remained unmethylated in all cases. The level of methylation of the region located downstream of the coding region of the terc gene changes with age. This region was analyzed in the samples of other tissues, and its methylation status was also nonuniform. The alteration of the methylation status in the 3'-untranslated region of the terc gene suggests the possibility of transcription of the antisense strand in this region.
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Belova E. V. et al. DNA methylation of genes of the main components of the telomerase complex in Danio rerio // Doklady Biochemistry and Biophysics. 2015. Vol. 464. No. 1. pp. 329-332.
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Belova E. V., Kozlov A. E., Shubernetskaya O. S., Zvereva M. I., Shpanchenko O. V., Dontsova O. A. DNA methylation of genes of the main components of the telomerase complex in Danio rerio // Doklady Biochemistry and Biophysics. 2015. Vol. 464. No. 1. pp. 329-332.
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TY - JOUR
DO - 10.1134/S1607672915050166
UR - https://doi.org/10.1134%2FS1607672915050166
TI - DNA methylation of genes of the main components of the telomerase complex in Danio rerio
T2 - Doklady Biochemistry and Biophysics
AU - Belova, E. V.
AU - Kozlov, A E
AU - Shubernetskaya, O S
AU - Zvereva, M I
AU - Shpanchenko, O V
AU - Dontsova, O. A.
PY - 2015
DA - 2015/09/01 00:00:00
PB - Pleiades Publishing
SP - 329-332
IS - 1
VL - 464
SN - 1607-6729
SN - 1608-3091
ER -
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@article{2015_Belova
author = {E. V. Belova and A E Kozlov and O S Shubernetskaya and M I Zvereva and O V Shpanchenko and O. A. Dontsova},
title = {DNA methylation of genes of the main components of the telomerase complex in Danio rerio},
journal = {Doklady Biochemistry and Biophysics},
year = {2015},
volume = {464},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134%2FS1607672915050166},
number = {1},
pages = {329--332},
doi = {10.1134/S1607672915050166}
}
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Copy
Belova, E. V., et al. “DNA methylation of genes of the main components of the telomerase complex in Danio rerio.” Doklady Biochemistry and Biophysics, vol. 464, no. 1, Sep. 2015, pp. 329-332. https://doi.org/10.1134%2FS1607672915050166.
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