Synthesis and Membrane Transport of Serotonin in the Developing Ovarian Follicle of Mouse
Publication type: Journal Article
Publication date: 2018-01-01
scimago Q3
wos Q4
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
PubMed ID:
29536299
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract
Using RT-PCR, we showed the presence of Tph1 mRNA in follicular cells and Tph2 mRNA in oocytes isolated from primary multilayer ovarian follicles of mouse and the absence of Ddc expression, which indicates that serotonin cannot be synthesized in a developing ovarian follicle. The membrane serotonin transporter Sert is expressed in follicular cells and oocytes. Experiments on the cultivation of follicles in vitro confirmed the absence of serotonin synthesis from 5-hydroxytryptophan and the presence of membrane transport activity in the oocyte.
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Nikishin D. A. et al. Synthesis and Membrane Transport of Serotonin in the Developing Ovarian Follicle of Mouse // Doklady Biochemistry and Biophysics. 2018. Vol. 478. No. 1. pp. 4-7.
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Nikishin D. A., Alyoshina N. M., Shmukler Y. B. Synthesis and Membrane Transport of Serotonin in the Developing Ovarian Follicle of Mouse // Doklady Biochemistry and Biophysics. 2018. Vol. 478. No. 1. pp. 4-7.
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RIS
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TY - JOUR
DO - 10.1134/S1607672918010027
UR - https://doi.org/10.1134/S1607672918010027
TI - Synthesis and Membrane Transport of Serotonin in the Developing Ovarian Follicle of Mouse
T2 - Doklady Biochemistry and Biophysics
AU - Nikishin, D A
AU - Alyoshina, N M
AU - Shmukler, Y B
PY - 2018
DA - 2018/01/01
PB - Pleiades Publishing
SP - 4-7
IS - 1
VL - 478
PMID - 29536299
SN - 1607-6729
SN - 1608-3091
ER -
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BibTex (up to 50 authors)
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@article{2018_Nikishin,
author = {D A Nikishin and N M Alyoshina and Y B Shmukler},
title = {Synthesis and Membrane Transport of Serotonin in the Developing Ovarian Follicle of Mouse},
journal = {Doklady Biochemistry and Biophysics},
year = {2018},
volume = {478},
publisher = {Pleiades Publishing},
month = {jan},
url = {https://doi.org/10.1134/S1607672918010027},
number = {1},
pages = {4--7},
doi = {10.1134/S1607672918010027}
}
Cite this
MLA
Copy
Nikishin, D. A., et al. “Synthesis and Membrane Transport of Serotonin in the Developing Ovarian Follicle of Mouse.” Doklady Biochemistry and Biophysics, vol. 478, no. 1, Jan. 2018, pp. 4-7. https://doi.org/10.1134/S1607672918010027.