Pleiades Publishing
Doklady Biochemistry and Biophysics
,  том 493 ,  издание 1 ,  страницы 181-184

Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver

Тип публикации: Journal Article
Дата публикации: 2020-07-01
Pleiades Publishing
scimago Q3
wos Q4
БС3
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
General Chemistry
Biochemistry
General Medicine
Biophysics
Краткое описание
Long noncoding RNAs (lncRNAs) are promising biomarkers and potential targets for liver cancer therapy. Stable hepatocyte lines are used in vitro to investigate functions of lncRNAs which amount in cell fluctuates during carcinogenesis. For the first time we compared gene expression of known lncRNAs in human conditional normal liver cells HepaRG and cancer cell lines Huh7 and HepG2. We showed that relative amounts of these lncRNAs in HepaRG are close to analogous variables measured for liver samples from healthy donors. Obtained data demonstrate exclusive peculiarities of HepaRG and confirm its reasonable application as a model of normal human hepatocytes for studying functions of lncRNAs.
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Burenina O. Y. et al. Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver // Doklady Biochemistry and Biophysics. 2020. Vol. 493. No. 1. pp. 181-184.
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Burenina O. Y., Zatsepin T. S., Kim E. F., Metelin A. V., Skvortsov D. A., Rubtsova M. P., Dontsova O. A. Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver // Doklady Biochemistry and Biophysics. 2020. Vol. 493. No. 1. pp. 181-184.
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TY - JOUR
DO - 10.1134/S1607672920040043
UR - https://link.springer.com/10.1134/S1607672920040043
TI - Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver
T2 - Doklady Biochemistry and Biophysics
AU - Burenina, O Y
AU - Zatsepin, T S
AU - Kim, E F
AU - Metelin, A V
AU - Skvortsov, D A
AU - Rubtsova, M. P.
AU - Dontsova, O. A.
PY - 2020
DA - 2020/07/01
PB - Pleiades Publishing
SP - 181-184
IS - 1
VL - 493
PMID - 32894460
SN - 1607-6729
SN - 1608-3091
ER -
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@article{2020_Burenina,
author = {O Y Burenina and T S Zatsepin and E F Kim and A V Metelin and D A Skvortsov and M. P. Rubtsova and O. A. Dontsova},
title = {Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver},
journal = {Doklady Biochemistry and Biophysics},
year = {2020},
volume = {493},
publisher = {Pleiades Publishing},
month = {jul},
url = {https://link.springer.com/10.1134/S1607672920040043},
number = {1},
pages = {181--184},
doi = {10.1134/S1607672920040043}
}
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Burenina, O. Y., et al. “Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver.” Doklady Biochemistry and Biophysics, vol. 493, no. 1, Jul. 2020, pp. 181-184. https://link.springer.com/10.1134/S1607672920040043.