Pleiades Publishing
Doklady Biochemistry and Biophysics
,  volume 505 ,  issue 1 ,  pages 137-140

Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines

Publication type: Journal Article
Publication date: 2022-08-29
Pleiades Publishing
scimago Q3
wos Q4
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract

A lot of long non-coding RNAs (lncRNAs) are expressed in human cells in a number of transcripts of different lengths and composition of exons. In case of cancer-associated lncRNAs, an actual task is to determine their specific isoforms, since each transcript can perform its own function in carcinogenesis and might have a unique expression profile in various types of tumors. For the first time, we analyzed the expression of CASC8 lncRNA in human pancreatic ductal adenocarcinoma cell lines and found an abundant isoform that was previously considered as the minor one in this type of cancer. We also revealed extremely high expression levels of all CASC8 transcripts in MIA PaCa-2 cells and, conversely, the lack of this lncRNA in PANC-1. This allows to use them as convenient models for further in vitro studies.

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Burenina O. Y. et al. Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines // Doklady Biochemistry and Biophysics. 2022. Vol. 505. No. 1. pp. 137-140.
GOST all authors (up to 50) Copy
Burenina O. Y., Lazarevich N. L., Kustova I. F., Zatsepin T. S., Rubtsova M. P., Dontsova O. A. Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines // Doklady Biochemistry and Biophysics. 2022. Vol. 505. No. 1. pp. 137-140.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/S1607672922040020
UR - https://link.springer.com/10.1134/S1607672922040020
TI - Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines
T2 - Doklady Biochemistry and Biophysics
AU - Burenina, O Y
AU - Lazarevich, N L
AU - Kustova, I F
AU - Zatsepin, T S
AU - Rubtsova, M. P.
AU - Dontsova, O. A.
PY - 2022
DA - 2022/08/29
PB - Pleiades Publishing
SP - 137-140
IS - 1
VL - 505
PMID - 36038677
SN - 1607-6729
SN - 1608-3091
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Burenina,
author = {O Y Burenina and N L Lazarevich and I F Kustova and T S Zatsepin and M. P. Rubtsova and O. A. Dontsova},
title = {Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines},
journal = {Doklady Biochemistry and Biophysics},
year = {2022},
volume = {505},
publisher = {Pleiades Publishing},
month = {aug},
url = {https://link.springer.com/10.1134/S1607672922040020},
number = {1},
pages = {137--140},
doi = {10.1134/S1607672922040020}
}
MLA
Cite this
MLA Copy
Burenina, O. Y., et al. “Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines.” Doklady Biochemistry and Biophysics, vol. 505, no. 1, Aug. 2022, pp. 137-140. https://link.springer.com/10.1134/S1607672922040020.