Doklady Biochemistry and Biophysics, том 505, издание 1, номера страниц: 137-140

Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines

Тип документаJournal Article
Дата публикации2022-08
ИздательPleiades Publishing
Название журналаDoklady Biochemistry and Biophysics
Квартиль по SCImagoQ3
Квартиль по Web of ScienceQ4
Импакт-фактор 20210.83
ISSN16076729, 16083091
General Chemistry
General Medicine
Краткое описание

A lot of long non-coding RNAs (lncRNAs) are expressed in human cells in a number of transcripts of different lengths and composition of exons. In case of cancer-associated lncRNAs, an actual task is to determine their specific isoforms, since each transcript can perform its own function in carcinogenesis and might have a unique expression profile in various types of tumors. For the first time, we analyzed the expression of CASC8 lncRNA in human pancreatic ductal adenocarcinoma cell lines and found an abundant isoform that was previously considered as the minor one in this type of cancer. We also revealed extremely high expression levels of all CASC8 transcripts in MIA PaCa-2 cells and, conversely, the lack of this lncRNA in PANC-1. This allows to use them as convenient models for further in vitro studies.

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1. Burenina O. Y. и др. Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines // Doklady Biochemistry and Biophysics. 2022. Т. 505. № 1. С. 137–140.


DO - 10.1134/s1607672922040020

UR -

TI - Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines

T2 - Doklady Biochemistry and Biophysics

AU - Burenina, O. Y.

AU - Lazarevich, N. L.

AU - Kustova, I. F.

AU - Zatsepin, T. S.

AU - Rubtsova, M. P.

AU - Dontsova, O. A.

PY - 2022

DA - 2022/08

PB - Pleiades Publishing Ltd

SP - 137-140

IS - 1

VL - 505

SN - 1607-6729

SN - 1608-3091

ER -

BibTex |


doi = {10.1134/s1607672922040020},

url = {},

year = 2022,

month = {aug},

publisher = {Pleiades Publishing Ltd},

volume = {505},

number = {1},

pages = {137--140},

author = {O. Y. Burenina and N. L. Lazarevich and I. F. Kustova and T. S. Zatsepin and M. P. Rubtsova and O. A. Dontsova},

title = {Expression of {CASC}8 {RNA} in Human Pancreatic Cancer Cell Lines},

journal = {Doklady Biochemistry and Biophysics}


Burenina, O. Y., et al. “Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines.” Doklady Biochemistry and Biophysics, vol. 505, no. 1, Aug. 2022, pp. 137–40. Crossref,