Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry

, том 4 , издание 2 , страницы 177-183

Biodegradation kinetics of poly(3-hydroxybutyrate)-based biopolymer systems

A P Boskhomdzhiev ¹

A. P. Bonartsev ^{1, 2}

T. K. Makhina ¹

V. L. Myshkina ¹

E. A. Ivanov ¹

D V Bagrov ²

E V Filatova ¹

A. L. Iordanskii ^{1, 3}

G. A. Bonartseva ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 3 аффилиации

A. N. Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, Russia |

Faculty of Biology, M. V. Lomonosov Moscow State University, Moscow, Russia |

N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia |

Тип публикации: Journal Article

Дата публикации: 2010-05-23

Pleiades Publishing

Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry

scimago Q4

wos Q4

БС3

SJR: 0.206

CiteScore: 1.0

Impact factor: 0.4

ISSN: 19907508, 19907516

DOI: 10.1134/S1990750810020083

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Biochemistry

Clinical Biochemistry

Molecular Medicine

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The aim of this study was to evaluate and to compare the long-term kinetics curves of biodegradation of poly(3-hydroxybutyrate) (PHB), its copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate), and a PHB/polylactic acid composite. The total weight loss and the change of average viscosity molecular weight were used as the parameters reflecting the biodegradation degree. The rate of biodegradation was analyzed in vitro in the presence of lipase and in vivo after film implantation in animal tissues. The morphology of the PHB film surface was studied by the atomic force microscopy technique. It was shown that PHB biodegradation involves both polymer hydrolysis and its enzymatic biodegradation. The results obtained in this study can be used for the development of various PHB-based medical devices.

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Boskhomdzhiev A. P. et al. Biodegradation kinetics of poly(3-hydroxybutyrate)-based biopolymer systems // Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 2010. Vol. 4. No. 2. pp. 177-183.

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Boskhomdzhiev A. P., Bonartsev A. P., Makhina T. K., Myshkina V. L., Ivanov E. A., Bagrov D. V., Filatova E. V., Iordanskii A. L., Bonartseva G. A. Biodegradation kinetics of poly(3-hydroxybutyrate)-based biopolymer systems // Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 2010. Vol. 4. No. 2. pp. 177-183.

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TY - JOUR

DO - 10.1134/S1990750810020083

UR - https://doi.org/10.1134/S1990750810020083

TI - Biodegradation kinetics of poly(3-hydroxybutyrate)-based biopolymer systems

T2 - Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry

AU - Boskhomdzhiev, A P

AU - Bonartsev, A. P.

AU - Makhina, T. K.

AU - Myshkina, V. L.

AU - Ivanov, E. A.

AU - Bagrov, D V

AU - Filatova, E V

AU - Iordanskii, A. L.

AU - Bonartseva, G. A.

PY - 2010

DA - 2010/05/23

PB - Pleiades Publishing

SP - 177-183

IS - 2

VL - 4

SN - 1990-7508

SN - 1990-7516

ER -

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@article{2010_Boskhomdzhiev,

author = {A P Boskhomdzhiev and A. P. Bonartsev and T. K. Makhina and V. L. Myshkina and E. A. Ivanov and D V Bagrov and E V Filatova and A. L. Iordanskii and G. A. Bonartseva},

title = {Biodegradation kinetics of poly(3-hydroxybutyrate)-based biopolymer systems},

journal = {Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry},

year = {2010},

volume = {4},

publisher = {Pleiades Publishing},

month = {may},

url = {https://doi.org/10.1134/S1990750810020083},

number = {2},

pages = {177--183},

doi = {10.1134/S1990750810020083}

}

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Boskhomdzhiev, A. P., et al. “Biodegradation kinetics of poly(3-hydroxybutyrate)-based biopolymer systems.” Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, vol. 4, no. 2, May. 2010, pp. 177-183. https://doi.org/10.1134/S1990750810020083.