, том 16 , издание 4 , страницы 439-449

The Possibilities of Modification of Particles Based on Lactide/Glycolide Copolymers by the Layer-by-Layer Adsorption of Polyelectrolytes for Designing the Tools for Targeted Drug Delivery

T.V. Bukreeva ^{1, 2}

I V Marchenko ^{1, 2}

O I Timaeva ¹

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Kurchatov Institute National Research Center, Moscow, Russia |

Shubnikov Institute of Crystalography of Federal Scientific Research Center Crystallography and Photonics of the Russian Academy of Sciences, Moscow, Russia

Курчатовский комплекс "Кристаллография и Фотоника"

Институт кристаллографии имени А. В. Шубникова

Тип публикации: Journal Article

Дата публикации: 2021-07-01

Pleiades Publishing

Nanobiotechnology Reports

scimago Q4

wos Q4

БС3

SJR: 0.150

CiteScore: 0.7

Impact factor: 0.5

ISSN: 26351676, 26351684

DOI: 10.1134/S2635167621040029

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Condensed Matter Physics

General Materials Science

Electrical and Electronic Engineering

Bioengineering

Biomedical Engineering

Engineering (miscellaneous)

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This review discusses the possibilities of the method of layer-by-layer adsorption of polyelectrolytes on colloidal particles used to design the tools for drug delivery and the studies of recent years on designing the carriers based on the particles of lactide/glycolide copolymers and a polyelectrolyte capsule for targeted drug delivery. The examples of inclusion of functional substances in the core or multilayer coating of carriers, as well as formation of complex systems containing different target agents in the core and the coating, are presented. The effects of the composition of polyelectrolyte coating on the properties of resultant particles were considered. The prospects of modification of lactide/glycolide copolymer particles by the layer-by-layer adsorption of polyelectrolytes for the development of new tools for targeted drug delivery were demonstrated.

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Курчатовский комплекс "Кристаллография и Фотоника"

Национальный исследовательский центр "Курчатовский институт"

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Институт синтетических полимерных материалов им. Н.С. Ениколопова РАН

Национальный исследовательский центр "Курчатовский институт"

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Высокомолекулярные соединения

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Малоугловое рентгеновское рассеяние (Small-angle X-ray scattering)

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Рентгеновская дифракция

Рентгеноструктурный анализ

Самозаживляющиеся полимеры (self-healing polymers)

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Bukreeva T. et al. The Possibilities of Modification of Particles Based on Lactide/Glycolide Copolymers by the Layer-by-Layer Adsorption of Polyelectrolytes for Designing the Tools for Targeted Drug Delivery // Nanobiotechnology Reports. 2021. Vol. 16. No. 4. pp. 439-449.

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Bukreeva T., Marchenko I. V., Timaeva O. I. The Possibilities of Modification of Particles Based on Lactide/Glycolide Copolymers by the Layer-by-Layer Adsorption of Polyelectrolytes for Designing the Tools for Targeted Drug Delivery // Nanobiotechnology Reports. 2021. Vol. 16. No. 4. pp. 439-449.

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TY - JOUR

DO - 10.1134/S2635167621040029

UR - https://doi.org/10.1134/S2635167621040029

TI - The Possibilities of Modification of Particles Based on Lactide/Glycolide Copolymers by the Layer-by-Layer Adsorption of Polyelectrolytes for Designing the Tools for Targeted Drug Delivery

T2 - Nanobiotechnology Reports

AU - Bukreeva, T.V.

AU - Marchenko, I V

AU - Timaeva, O I

PY - 2021

DA - 2021/07/01

PB - Pleiades Publishing

SP - 439-449

IS - 4

VL - 16

SN - 2635-1676

SN - 2635-1684

ER -

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@article{2021_Bukreeva,

author = {T.V. Bukreeva and I V Marchenko and O I Timaeva},

title = {The Possibilities of Modification of Particles Based on Lactide/Glycolide Copolymers by the Layer-by-Layer Adsorption of Polyelectrolytes for Designing the Tools for Targeted Drug Delivery},

journal = {Nanobiotechnology Reports},

year = {2021},

volume = {16},

publisher = {Pleiades Publishing},

month = {jul},

url = {https://doi.org/10.1134/S2635167621040029},

number = {4},

pages = {439--449},

doi = {10.1134/S2635167621040029}

}

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Bukreeva, T.V., et al. “The Possibilities of Modification of Particles Based on Lactide/Glycolide Copolymers by the Layer-by-Layer Adsorption of Polyelectrolytes for Designing the Tools for Targeted Drug Delivery.” Nanobiotechnology Reports, vol. 16, no. 4, Jul. 2021, pp. 439-449. https://doi.org/10.1134/S2635167621040029.