Pleiades Publishing
Russian Journal of General Chemistry
,  том 91 ,  издание 9 ,  страницы 1661-1666

Synthesis and Chromatographic Analysis of the Neuroprotective Agent Mafedine and Related Compounds

Тип публикации: Journal Article
Дата публикации: 2021-09-01
Pleiades Publishing
scimago Q4
wos Q4
БС2
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Краткое описание
A procedure for the synthesis of 2-anilino-6-hydroxy-3-phenylpyrimidin-4(3H)-one (mafedine) without using alkali metal ethoxides has been developed and optimized. Mafedine-related compounds that can be formed as possible impurities have been prepared, and conditions for joint determination of these impurities by HPLC with spectrophotometric detection have been found. The structure of the mafedine decomposition product in solution has been identified by HPLC-ESI/MS.
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Sipkina N. Yu. et al. Synthesis and Chromatographic Analysis of the Neuroprotective Agent Mafedine and Related Compounds // Russian Journal of General Chemistry. 2021. Vol. 91. No. 9. pp. 1661-1666.
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Sipkina N. Yu., Yuskovets V. N., Chernov N. M., Starova G. L., Yakovlev I. P. Synthesis and Chromatographic Analysis of the Neuroprotective Agent Mafedine and Related Compounds // Russian Journal of General Chemistry. 2021. Vol. 91. No. 9. pp. 1661-1666.
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TY - JOUR
DO - 10.1134/s1070363221090085
UR - https://doi.org/10.1134/s1070363221090085
TI - Synthesis and Chromatographic Analysis of the Neuroprotective Agent Mafedine and Related Compounds
T2 - Russian Journal of General Chemistry
AU - Sipkina, N Yu
AU - Yuskovets, V N
AU - Chernov, N M
AU - Starova, G L
AU - Yakovlev, I P
PY - 2021
DA - 2021/09/01
PB - Pleiades Publishing
SP - 1661-1666
IS - 9
VL - 91
SN - 1070-3632
SN - 1608-3350
ER -
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@article{2021_Sipkina,
author = {N Yu Sipkina and V N Yuskovets and N M Chernov and G L Starova and I P Yakovlev},
title = {Synthesis and Chromatographic Analysis of the Neuroprotective Agent Mafedine and Related Compounds},
journal = {Russian Journal of General Chemistry},
year = {2021},
volume = {91},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/s1070363221090085},
number = {9},
pages = {1661--1666},
doi = {10.1134/s1070363221090085}
}
MLA
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Sipkina, N. Yu., et al. “Synthesis and Chromatographic Analysis of the Neuroprotective Agent Mafedine and Related Compounds.” Russian Journal of General Chemistry, vol. 91, no. 9, Sep. 2021, pp. 1661-1666. https://doi.org/10.1134/s1070363221090085.
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