Open Access

Journal of the American Heart Association, volume 10, issue 22

Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study

Lulin Wang ^{1, 2}

Lulu Song ^{1, 2}

Dankang Li ^{1, 2}

Ziyi Zhou ^{1, 2}

Shuohua Chen ³

Yingping Yang ^{1, 2}

Yonghua Hu ⁴

Youjie Wang ^{1, 2}

Shou-Ling Wu ³

Yaohua Tian ^{1, 2}

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Department of Maternal and Child Health School of Public Health Tongji Medical CollegeHuazhong University of Science and Technology Wuhan China |

Ministry of Education Key Laboratory of Environment and Health, and State Key Laboratory of Environmental Health (Incubating) School of Public Health Tongji Medical CollegeHuazhong University of Science and Technology Wuhan China |

Department of Cardiology Kailuan General Hospital North China University of Science and Technology Tangshan City China |

⁴

Department of Epidemiology and Biostatistics School of Public Health Peking University Beijing China |

Publication type: Journal Article

Publication date: 2021-11-10

Wiley

Journal: Journal of the American Heart Association

scimago Q1

SJR: 2.126

CiteScore: 9.4

Impact factor: 5

ISSN: 20479980

DOI: 10.1161/JAHA.121.022502

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Cardiology and Cardiovascular Medicine

Abstract

Background

Cardiovascular health (CVH) status is associated with cardiovascular diseases (CVD). However, evidence for association of CVH change with risk of CVD is scarce.

Methods and Results

Seven metrics (smoking status, body mass index, physical activity, diet, total cholesterol, blood pressure, and fasting blood glucose) were used to evaluate the CVH status. Having 0 to 2, 3 to 4, and 5 to 7 ideal cardiovascular metrics were categorized as low, moderate, and high CVH status, respectively. Change in CVH status was assessed from 2006/2007 to 2010/2011. We calculated lifetime risk of CVD using a modified Kaplan–Meier method, and life expectancy was evaluated via the multistate lifetable method. There were 82 349 participants included in our analysis. At 35 years index age, the age‐adjusted incident rate and lifetime risk of CVD were increased with decreasing number of ideal CVH metrics. The direction of change in status of CVH was consistently associated with age‐adjusted incident rate and lifetime risk of CVD. At 35 years index age, improvement from low to moderate (37.6% [95% CI, 32.8%–42.4%]) or to high status (24.4% [95% CI, 12.7%–36.0%]) had lower lifetime risk of CVD compared with consistently low status (44.6% [95% CI, 40.8%–48.5%]). The improvement in CVH could prolong the years of life free from CVD. The pattern of incident rate and lifetime risk across change in CVH status was similar at 45 and 55 years index age.

Conclusions

Higher number of CVH metrics was associated with lower lifetime risk of CVD. The improvement of CVH status could reduce the lifetime risk of CVD and prolonged the year of life free from CVD.

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Publisher

Wiley

Journal

Journal of the American Heart Association

scimago Q1

SJR

2.126

CiteScore

9.4

Impact factor

ISSN

20479980 (Print, Electronic)

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Chen, Shuohua

Ideal Cardiovascular Health Metric and Its Change With Lifetime Risk of Cardiovascular Diseases: A Prospective Cohort Study

Background

Methods and Results

Conclusions

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