Open Access
Nanomedicine for increasing the oral bioavailability of cancer treatments
Alessandro Parodi
1, 2
,
Polina Buzaeva
1
,
Daria Nigovora
1
,
Alexey Baldin
3
,
Dmitry Kostyushev
2, 4
,
Vladimir Chulanov
2, 4, 5
,
Lyudmila V. Savvateeva
1
,
Andrey A. Zamyatnin
1, 2, 3, 6
3
4
National Medical Research Center of Tuberculosis and Infectious Diseases, Ministry of Health, Moscow, Russia
|
Тип публикации: Journal Article
Дата публикации: 2021-10-30
scimago Q1
wos Q1
БС1
SJR: 2.282
CiteScore: 16.8
Impact factor: 12.6
ISSN: 14773155
PubMed ID:
34717658
Medicine (miscellaneous)
Pharmaceutical Science
Molecular Medicine
Applied Microbiology and Biotechnology
Bioengineering
Biomedical Engineering
Краткое описание
Oral administration is an appealing route of delivering cancer treatments. However, the gastrointestinal tract is characterized by specific and efficient physical, chemical, and biological barriers that decrease the bioavailability of medications, including chemotherapeutics. In recent decades, the fields of material science and nanomedicine have generated several delivery platforms with high potential for overcoming multiple barriers associated to oral administration. This review describes the properties of several nanodelivery systems that improve the bioavailability of orally administered therapeutics, highlighting their advantages and disadvantages in generating successful anticancer oral nanomedicines.
Graphical Abstract
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(52.7%)
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ГОСТ |
RIS |
BibTex
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ГОСТ
Скопировать
Parodi A. et al. Nanomedicine for increasing the oral bioavailability of cancer treatments // Journal of Nanobiotechnology. 2021. Vol. 19. No. 1. 354
ГОСТ со всеми авторами (до 50)
Скопировать
Parodi A., Buzaeva P., Nigovora D., Baldin A., Kostyushev D., Chulanov V., Savvateeva L. V., Zamyatnin A. A. Nanomedicine for increasing the oral bioavailability of cancer treatments // Journal of Nanobiotechnology. 2021. Vol. 19. No. 1. 354
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RIS
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TY - JOUR
DO - 10.1186/s12951-021-01100-2
UR - https://doi.org/10.1186/s12951-021-01100-2
TI - Nanomedicine for increasing the oral bioavailability of cancer treatments
T2 - Journal of Nanobiotechnology
AU - Parodi, Alessandro
AU - Buzaeva, Polina
AU - Nigovora, Daria
AU - Baldin, Alexey
AU - Kostyushev, Dmitry
AU - Chulanov, Vladimir
AU - Savvateeva, Lyudmila V.
AU - Zamyatnin, Andrey A.
PY - 2021
DA - 2021/10/30
PB - Springer Nature
IS - 1
VL - 19
PMID - 34717658
SN - 1477-3155
ER -
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BibTex (до 50 авторов)
Скопировать
@article{2021_Parodi,
author = {Alessandro Parodi and Polina Buzaeva and Daria Nigovora and Alexey Baldin and Dmitry Kostyushev and Vladimir Chulanov and Lyudmila V. Savvateeva and Andrey A. Zamyatnin},
title = {Nanomedicine for increasing the oral bioavailability of cancer treatments},
journal = {Journal of Nanobiotechnology},
year = {2021},
volume = {19},
publisher = {Springer Nature},
month = {oct},
url = {https://doi.org/10.1186/s12951-021-01100-2},
number = {1},
pages = {354},
doi = {10.1186/s12951-021-01100-2}
}
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