Open Access
Nanomedicine for increasing the oral bioavailability of cancer treatments
Alessandro Parodi
1, 2
,
Polina Buzaeva
1
,
Daria Nigovora
1
,
Alexey Baldin
3
,
Dmitry Kostyushev
2, 4
,
Vladimir Chulanov
2, 4, 5
,
Lyudmila V. Savvateeva
1
,
Andrey A. Zamyatnin
1, 2, 3, 6
3
4
National Medical Research Center of Tuberculosis and Infectious Diseases, Ministry of Health, Moscow, Russia
|
Publication type: Journal Article
Publication date: 2021-10-30
scimago Q1
wos Q1
SJR: 2.282
CiteScore: 16.8
Impact factor: 12.6
ISSN: 14773155
PubMed ID:
34717658
Medicine (miscellaneous)
Pharmaceutical Science
Molecular Medicine
Applied Microbiology and Biotechnology
Bioengineering
Biomedical Engineering
Abstract
Oral administration is an appealing route of delivering cancer treatments. However, the gastrointestinal tract is characterized by specific and efficient physical, chemical, and biological barriers that decrease the bioavailability of medications, including chemotherapeutics. In recent decades, the fields of material science and nanomedicine have generated several delivery platforms with high potential for overcoming multiple barriers associated to oral administration. This review describes the properties of several nanodelivery systems that improve the bioavailability of orally administered therapeutics, highlighting their advantages and disadvantages in generating successful anticancer oral nanomedicines.
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Metrics
74
Total citations:
74
Citations from 2024:
39
(52%)
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Parodi A. et al. Nanomedicine for increasing the oral bioavailability of cancer treatments // Journal of Nanobiotechnology. 2021. Vol. 19. No. 1. 354
GOST all authors (up to 50)
Copy
Parodi A., Buzaeva P., Nigovora D., Baldin A., Kostyushev D., Chulanov V., Savvateeva L. V., Zamyatnin A. A. Nanomedicine for increasing the oral bioavailability of cancer treatments // Journal of Nanobiotechnology. 2021. Vol. 19. No. 1. 354
Cite this
RIS
Copy
TY - JOUR
DO - 10.1186/s12951-021-01100-2
UR - https://doi.org/10.1186/s12951-021-01100-2
TI - Nanomedicine for increasing the oral bioavailability of cancer treatments
T2 - Journal of Nanobiotechnology
AU - Parodi, Alessandro
AU - Buzaeva, Polina
AU - Nigovora, Daria
AU - Baldin, Alexey
AU - Kostyushev, Dmitry
AU - Chulanov, Vladimir
AU - Savvateeva, Lyudmila V.
AU - Zamyatnin, Andrey A.
PY - 2021
DA - 2021/10/30
PB - Springer Nature
IS - 1
VL - 19
PMID - 34717658
SN - 1477-3155
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Parodi,
author = {Alessandro Parodi and Polina Buzaeva and Daria Nigovora and Alexey Baldin and Dmitry Kostyushev and Vladimir Chulanov and Lyudmila V. Savvateeva and Andrey A. Zamyatnin},
title = {Nanomedicine for increasing the oral bioavailability of cancer treatments},
journal = {Journal of Nanobiotechnology},
year = {2021},
volume = {19},
publisher = {Springer Nature},
month = {oct},
url = {https://doi.org/10.1186/s12951-021-01100-2},
number = {1},
pages = {354},
doi = {10.1186/s12951-021-01100-2}
}
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