Open Access
Open access
Biomaterials Research, volume 24, issue 1, publication number 6

Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis

Publication typeJournal Article
Publication date2020-02-04
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor11.3
ISSN20557124
Ceramics and Composites
Medicine (miscellaneous)
Biomaterials
Biomedical Engineering
Abstract
The electrochemical biosensor is one of the typical sensing devices based on transducing the biochemical events to electrical signals. In this type of sensor, an electrode is a key component that is employed as a solid support for immobilization of biomolecules and electron movement. Thanks to numerous nanomaterials that possess the large surface area, synergic effects are enabled by improving loading capacity and the mass transport of reactants for achieving high performance in terms of analytical sensitivity. We categorized the current electrochemical biosensors into two groups, carbon-based (carbon nanotubes and graphene) and non-carbon-based nanomaterials (metallic and silica nanoparticles, nanowire, and indium tin oxide, organic materials). The carbon allotropes can be employed as an electrode and supporting scaffolds due to their large active surface area as well as an effective electron transfer rate. We also discussed the non-carbon nanomaterials that are used as alternative supporting components of the electrode for improving the electrochemical properties of biosensors. Although several functional nanomaterials have provided the innovative solid substrate for high performances, developing on-site version of biosensor that meets enough sensitivity along with high reproducibility still remains a challenge. In particular, the matrix interference from real samples which seriously affects the biomolecular interaction still remains the most critical issues that need to be solved for practical aspect in the electrochemical biosensor.

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GOST Copy
Cho I. H., Kim D., Park S. Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis // Biomaterials Research. 2020. Vol. 24. No. 1. 6
GOST all authors (up to 50) Copy
Cho I. H., Kim D., Park S. Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis // Biomaterials Research. 2020. Vol. 24. No. 1. 6
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RIS Copy
TY - JOUR
DO - 10.1186/s40824-019-0181-y
UR - https://doi.org/10.1186/s40824-019-0181-y
TI - Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis
T2 - Biomaterials Research
AU - Cho, Il Hoon
AU - Kim, Dong-Hyung
AU - Park, Sangsoo
PY - 2020
DA - 2020/02/04 00:00:00
PB - Springer Nature
IS - 1
VL - 24
SN - 2055-7124
ER -
BibTex
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BibTex Copy
@article{2020_Cho,
author = {Il Hoon Cho and Dong-Hyung Kim and Sangsoo Park},
title = {Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis},
journal = {Biomaterials Research},
year = {2020},
volume = {24},
publisher = {Springer Nature},
month = {feb},
url = {https://doi.org/10.1186/s40824-019-0181-y},
number = {1},
doi = {10.1186/s40824-019-0181-y}
}
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