том 14 издание 1 страницы 133-141

Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review

Тип публикацииJournal Article
Дата публикации2012-01-27
SCImago Q1
Tоп 10% SCImago
WOS Q2
БС2
SJR0.81
CiteScore9.3
Impact factor3.7
ISSN15507416
Pharmaceutical Science
Краткое описание
Structure-based virtual screening (SBVS) has been widely applied in early-stage drug discovery. From a problem-centric perspective, we reviewed the recent advances and applications in SBVS with a special focus on docking-based virtual screening. We emphasized the researchers’ practical efforts in real projects by understanding the ligand-target binding interactions as a premise. We also highlighted the recent progress in developing target-biased scoring functions by optimizing current generic scoring functions toward certain target classes, as well as in developing novel ones by means of machine learning techniques.
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ГОСТ |
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Cheng T. et al. Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review // AAPS Journal. 2012. Vol. 14. No. 1. pp. 133-141.
ГОСТ со всеми авторами (до 50) Скопировать
Cheng T., Li Qingliang Q., Zhou Z., Wang Y., Bryant S. H. Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review // AAPS Journal. 2012. Vol. 14. No. 1. pp. 133-141.
RIS |
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TY - JOUR
DO - 10.1208/s12248-012-9322-0
UR - http://link.springer.com/10.1208/s12248-012-9322-0
TI - Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review
T2 - AAPS Journal
AU - Cheng, Tiejun
AU - Li Qingliang, Qingliang
AU - Zhou, Zhigang
AU - Wang, Yanli
AU - Bryant, Stephen H.
PY - 2012
DA - 2012/01/27
PB - Springer Nature
SP - 133-141
IS - 1
VL - 14
PMID - 22281989
SN - 1550-7416
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2012_Cheng,
author = {Tiejun Cheng and Qingliang Li Qingliang and Zhigang Zhou and Yanli Wang and Stephen H. Bryant},
title = {Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review},
journal = {AAPS Journal},
year = {2012},
volume = {14},
publisher = {Springer Nature},
month = {jan},
url = {http://link.springer.com/10.1208/s12248-012-9322-0},
number = {1},
pages = {133--141},
doi = {10.1208/s12248-012-9322-0}
}
MLA
Цитировать
Cheng, Tiejun, et al. “Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review.” AAPS Journal, vol. 14, no. 1, Jan. 2012, pp. 133-141. http://link.springer.com/10.1208/s12248-012-9322-0.
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