Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase.
1
Graduate School of Medicine Dentistry and Pharmaceutical Sciences
Publication type: Journal Article
Publication date: 2011-12-08
scimago Q3
wos Q3
SJR: 0.349
CiteScore: 2.7
Impact factor: 1.3
ISSN: 00092363, 13475223
PubMed ID:
2632045
General Chemistry
Drug Discovery
General Medicine
Abstract
An anti-HIV (human immunodeficiency virus) phenolic constituent, licopyranocoumarin (4), and two other new phenolics named licoarylcoumarin (5) and glisoflavone (6) were isolated from Si-pei licorice (a commercial licorice; root and stolon of Glycyrrhiza sp. from the north-western region of China) using droplet countercurrent chromatography and centrifugal partition chromatography, and their structures were assigned based on chemical and spectroscopic data. Kaempferol 3-O-methyl ether (7) and licocoumarone (8) were also isolated from the licorice. The inhibitory effects of ten licorice phenolics on xanthine oxidase were examined. Licochalcone B (1), glycyrrhisoflavone (2), 8 and licochalcone A (19) showed 50% inhibition at the concentration of 1.3-5.6 x 10(-5) M.
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Total citations:
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Hatano T. et al. Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase. // Chemical and Pharmaceutical Bulletin. 2011. Vol. 37. No. 11. pp. 3005-3009.
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Hatano T., YASUHARA T., Fukuda T., Okuda T. Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase. // Chemical and Pharmaceutical Bulletin. 2011. Vol. 37. No. 11. pp. 3005-3009.
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TY - JOUR
DO - 10.1248/cpb.37.3005
UR - https://doi.org/10.1248/cpb.37.3005
TI - Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase.
T2 - Chemical and Pharmaceutical Bulletin
AU - Hatano, T
AU - YASUHARA, Taeko
AU - Fukuda, Toshiyuki
AU - Okuda, Takuo
PY - 2011
DA - 2011/12/08
PB - Pharmaceutical Society of Japan
SP - 3005-3009
IS - 11
VL - 37
PMID - 2632045
SN - 0009-2363
SN - 1347-5223
ER -
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BibTex (up to 50 authors)
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@article{2011_Hatano,
author = {T Hatano and Taeko YASUHARA and Toshiyuki Fukuda and Takuo Okuda},
title = {Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase.},
journal = {Chemical and Pharmaceutical Bulletin},
year = {2011},
volume = {37},
publisher = {Pharmaceutical Society of Japan},
month = {dec},
url = {https://doi.org/10.1248/cpb.37.3005},
number = {11},
pages = {3005--3009},
doi = {10.1248/cpb.37.3005}
}
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MLA
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Hatano, T., et al. “Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase..” Chemical and Pharmaceutical Bulletin, vol. 37, no. 11, Dec. 2011, pp. 3005-3009. https://doi.org/10.1248/cpb.37.3005.