Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp.
Xia Zhang
1
,
Hong-Yan Xu
1
,
Ai-Mei Huang
1
,
Lei Wang
1
,
Qiang Wang
1
,
Peng-Yun Cao
1, 2
,
Pei-Min Yang
1
1
Department of Pharmacy, People’s Hospital of Linzi District
Publication type: Journal Article
Publication date: 2016-04-22
scimago Q3
wos Q3
SJR: 0.349
CiteScore: 2.7
Impact factor: 1.3
ISSN: 00092363, 13475223
PubMed ID:
27109501
General Chemistry
Drug Discovery
General Medicine
Abstract
Chemical investigation of the sponge Dysidea sp. afforded three new sesquiterpene phenols (1-3) and one new sesquiterpene aminoquinone (4), together with four known sesquiterpene derivatives (5-8). The structures of all compounds were unambiguously elucidated by extensive spectroscopic analysis, as well as by comparison with the literature. The absolute configurations of compounds 1-4 were determined by electron capture detector (ECD) calculations and circular dichroism (CD) spectrum analysis. Their antibacterial activity against Escherichia coli (25922), Bacillus subtilis (6633), and Staphylococcus aureus (25923) were evaluated. Compounds 1 and 3 showed weak antibacterial activity against the above three strains, whereas compounds 4-8 showed potent antibacterial activities with minimum inhibitory concentration (MIC) values in the range of 3.125 to 12.5 µg/mL.
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GOST
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Zhang X. et al. Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp. // Chemical and Pharmaceutical Bulletin. 2016. Vol. 64. No. 7. pp. 1036-1042.
GOST all authors (up to 50)
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Zhang X., Xu H., Huang A., Wang L., Wang Q., Cao P., Yang P. Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp. // Chemical and Pharmaceutical Bulletin. 2016. Vol. 64. No. 7. pp. 1036-1042.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1248/cpb.c16-00183
UR - https://doi.org/10.1248/cpb.c16-00183
TI - Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp.
T2 - Chemical and Pharmaceutical Bulletin
AU - Zhang, Xia
AU - Xu, Hong-Yan
AU - Huang, Ai-Mei
AU - Wang, Lei
AU - Wang, Qiang
AU - Cao, Peng-Yun
AU - Yang, Pei-Min
PY - 2016
DA - 2016/04/22
PB - Pharmaceutical Society of Japan
SP - 1036-1042
IS - 7
VL - 64
PMID - 27109501
SN - 0009-2363
SN - 1347-5223
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Zhang,
author = {Xia Zhang and Hong-Yan Xu and Ai-Mei Huang and Lei Wang and Qiang Wang and Peng-Yun Cao and Pei-Min Yang},
title = {Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp.},
journal = {Chemical and Pharmaceutical Bulletin},
year = {2016},
volume = {64},
publisher = {Pharmaceutical Society of Japan},
month = {apr},
url = {https://doi.org/10.1248/cpb.c16-00183},
number = {7},
pages = {1036--1042},
doi = {10.1248/cpb.c16-00183}
}
Cite this
MLA
Copy
Zhang, Xia, et al. “Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp..” Chemical and Pharmaceutical Bulletin, vol. 64, no. 7, Apr. 2016, pp. 1036-1042. https://doi.org/10.1248/cpb.c16-00183.