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Biomedical Optics Express, volume 7, issue 4, pages 1193-1201

Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer

Palmer Scott 1
Litvinova Karina 2
Fleming Stewart 4
McGloin David 5
Nabi Ghulam 1
Publication typeJournal Article
Publication date2016-03-07
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor3.4
ISSN21567085
PubMed ID:  27446646
Biotechnology
Atomic and Molecular Physics, and Optics
Abstract
Muscle invasive urinary bladder cancer is one of the most lethal cancers and its detection at the time of transurethral resection remains limited and diagnostic methods are urgently needed. We have developed a muscle invasive transitional cell carcinoma (TCC) model of the bladder using porcine bladder scaffold and the human bladder cancer cell line 5637. The progression of implanted cancer cells to muscle invasion can be monitored by measuring changes in the spectrum of endogenous fluorophores such as reduced nicotinamide dinucleotide (NADH) and flavins. We believe this could act as a useful tool for the study of fluorescence dynamics of developing muscle invasive bladder cancer in patients.

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GOST |
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GOST Copy
Palmer S. et al. Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer // Biomedical Optics Express. 2016. Vol. 7. No. 4. pp. 1193-1201.
GOST all authors (up to 50) Copy
Palmer S., Litvinova K., Dunaev A., Fleming S., McGloin D., Nabi G. Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer // Biomedical Optics Express. 2016. Vol. 7. No. 4. pp. 1193-1201.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1364/BOE.7.001193
UR - https://doi.org/10.1364%2FBOE.7.001193
TI - Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer
T2 - Biomedical Optics Express
AU - Dunaev, Andrey
AU - McGloin, David
AU - Nabi, Ghulam
AU - Palmer, Scott
AU - Litvinova, Karina
AU - Fleming, Stewart
PY - 2016
DA - 2016/03/07 00:00:00
PB - Optical Society of America
SP - 1193-1201
IS - 4
VL - 7
PMID - 27446646
SN - 2156-7085
ER -
BibTex |
Cite this
BibTex Copy
@article{2016_Palmer,
author = {Andrey Dunaev and David McGloin and Ghulam Nabi and Scott Palmer and Karina Litvinova and Stewart Fleming},
title = {Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer},
journal = {Biomedical Optics Express},
year = {2016},
volume = {7},
publisher = {Optical Society of America},
month = {mar},
url = {https://doi.org/10.1364%2FBOE.7.001193},
number = {4},
pages = {1193--1201},
doi = {10.1364/BOE.7.001193}
}
MLA
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MLA Copy
Palmer, Scott, et al. “Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer.” Biomedical Optics Express, vol. 7, no. 4, Mar. 2016, pp. 1193-1201. https://doi.org/10.1364%2FBOE.7.001193.
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