Open Access
Porphyrin photosensitizers in photodynamic therapy and its applications
Publication type: Journal Article
Publication date: 2017-08-11
PubMed ID:
29113417
Oncology
Abstract
In 1841, the extraction of hematoporphyrin from dried blood by removing iron marked the birth of the photosensitizer. The last twenty years has witnessed extensive research in the application of photodynamic therapy (PDT) in tumor-bearing (or other diseases) animal models and patients. The period has seen development of photosensitizers from the first to the third generation, and their evolution from simple to more complex entities. This review focuses on porphyrin photosensitizers and their effect on tumors, mediated via several pathways involved in cell necrosis, apoptosis or autophagic cell death, and the preventive and therapeutic application of PDT against atherosclerosis.
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Metrics
494
Total citations:
494
Citations from 2025:
84
(17%)
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MLA
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GOST
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Kou J. et al. Porphyrin photosensitizers in photodynamic therapy and its applications // Oncotarget. 2017. Vol. 8. No. 46. pp. 81591-81603.
GOST all authors (up to 50)
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Kou J., Dou D., Yang L. Porphyrin photosensitizers in photodynamic therapy and its applications // Oncotarget. 2017. Vol. 8. No. 46. pp. 81591-81603.
Cite this
RIS
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TY - JOUR
DO - 10.18632/oncotarget.20189
UR - https://doi.org/10.18632/oncotarget.20189
TI - Porphyrin photosensitizers in photodynamic therapy and its applications
T2 - Oncotarget
AU - Kou, Jiayuan
AU - Dou, Dou
AU - Yang, Liming
PY - 2017
DA - 2017/08/11
PB - Impact Journals
SP - 81591-81603
IS - 46
VL - 8
PMID - 29113417
SN - 1949-2553
ER -
Cite this
BibTex (up to 50 authors)
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@article{2017_Kou,
author = {Jiayuan Kou and Dou Dou and Liming Yang},
title = {Porphyrin photosensitizers in photodynamic therapy and its applications},
journal = {Oncotarget},
year = {2017},
volume = {8},
publisher = {Impact Journals},
month = {aug},
url = {https://doi.org/10.18632/oncotarget.20189},
number = {46},
pages = {81591--81603},
doi = {10.18632/oncotarget.20189}
}
Cite this
MLA
Copy
Kou, Jiayuan, et al. “Porphyrin photosensitizers in photodynamic therapy and its applications.” Oncotarget, vol. 8, no. 46, Aug. 2017, pp. 81591-81603. https://doi.org/10.18632/oncotarget.20189.