5-Hydroxy-6-methyluracil, an Efficient Scavenger of Peroxyl Radical in Water
Publication type: Journal Article
Publication date: 2009-11-01
scimago Q3
wos Q3
SJR: 0.356
CiteScore: 4.0
Impact factor: 2.1
ISSN: 13852728, 18755348
Organic Chemistry
Abstract
The reactivity of 5-hydroxy-6-methyluracil (HMU) towards peroxyl radicals generated from the aerobic thermal decomposition of 2,2-azo-bis(2-amidinopropane)dihydrochloride (AAPH) has been investigated. The oxidation product of HMU is dihydro-5,5,6-trihydroxy-6-methylpyrimidin-2,4-dion-e (94%). The relative oxidation rate of HMU vs. quercetin by peroxyl radicals generated from AAPH has been measured as 0.20 ± 0.04 at 54.6°C, hence HMU is the effective scavenger of peroxyl radicals. The overall kinetic parameters and the efficiency of radical generation from AAPH in water solution at pH 7.0 (0.1 M phosphate buffer) have been determined using HMU in temperature range 26° - 84°C.
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13
Total citations:
13
Citations from 2024:
1
(7.69%)
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GOST
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Grabovskiy S. et al. 5-Hydroxy-6-methyluracil, an Efficient Scavenger of Peroxyl Radical in Water // Current Organic Chemistry. 2009. Vol. 13. No. 17. pp. 1733-1736.
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Grabovskiy S., Abdrakhmanova A., Murinov Y., Kabal'nova N. 5-Hydroxy-6-methyluracil, an Efficient Scavenger of Peroxyl Radical in Water // Current Organic Chemistry. 2009. Vol. 13. No. 17. pp. 1733-1736.
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RIS
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TY - JOUR
DO - 10.2174/138527209789578081
UR - https://doi.org/10.2174/138527209789578081
TI - 5-Hydroxy-6-methyluracil, an Efficient Scavenger of Peroxyl Radical in Water
T2 - Current Organic Chemistry
AU - Grabovskiy, S.
AU - Abdrakhmanova, A.
AU - Murinov, Y.
AU - Kabal'nova, N.
PY - 2009
DA - 2009/11/01
PB - Bentham Science Publishers Ltd.
SP - 1733-1736
IS - 17
VL - 13
SN - 1385-2728
SN - 1875-5348
ER -
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BibTex (up to 50 authors)
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@article{2009_Grabovskiy,
author = {S. Grabovskiy and A. Abdrakhmanova and Y. Murinov and N. Kabal'nova},
title = {5-Hydroxy-6-methyluracil, an Efficient Scavenger of Peroxyl Radical in Water},
journal = {Current Organic Chemistry},
year = {2009},
volume = {13},
publisher = {Bentham Science Publishers Ltd.},
month = {nov},
url = {https://doi.org/10.2174/138527209789578081},
number = {17},
pages = {1733--1736},
doi = {10.2174/138527209789578081}
}
Cite this
MLA
Copy
Grabovskiy, S., et al. “5-Hydroxy-6-methyluracil, an Efficient Scavenger of Peroxyl Radical in Water.” Current Organic Chemistry, vol. 13, no. 17, Nov. 2009, pp. 1733-1736. https://doi.org/10.2174/138527209789578081.
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