Tetraoxanes as antimalarials: harnessing the endoperoxide.
Publication type: Journal Article
Publication date: 2014-03-24
scimago Q2
wos Q3
SJR: 0.662
CiteScore: 8.5
Impact factor: 3.3
ISSN: 13895575, 18755607
PubMed ID:
24456270
Drug Discovery
General Medicine
Pharmacology
Abstract
With the emergence of resistance to artemesinin, the need for new antimalarial compounds is pressing. Several research groups have made significant contributions to the exploration of the use of 1,2,4,5-tetraoxanes and 1,2,4- trioxanes as synthetic analogues of artemesinin. This short review highlights the recent developments in this field detailing both biological results and useful synthetic methodology. In addition, the current understanding of the mode of action of this class of compounds has been described.
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25
Total citations:
25
Citations from 2024:
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(8%)
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MLA
Cite this
GOST
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Blackie M. A. Tetraoxanes as antimalarials: harnessing the endoperoxide. // Mini-Reviews in Medicinal Chemistry. 2014. Vol. 14. No. 2. pp. 123-135.
GOST all authors (up to 50)
Copy
Blackie M. A. Tetraoxanes as antimalarials: harnessing the endoperoxide. // Mini-Reviews in Medicinal Chemistry. 2014. Vol. 14. No. 2. pp. 123-135.
Cite this
RIS
Copy
TY - JOUR
DO - 10.2174/1389557514666140123144942
UR - https://doi.org/10.2174/1389557514666140123144942
TI - Tetraoxanes as antimalarials: harnessing the endoperoxide.
T2 - Mini-Reviews in Medicinal Chemistry
AU - Blackie, Margaret A.L.
PY - 2014
DA - 2014/03/24
PB - Bentham Science Publishers Ltd.
SP - 123-135
IS - 2
VL - 14
PMID - 24456270
SN - 1389-5575
SN - 1875-5607
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2014_Fisher,
author = {Margaret A.L. Blackie},
title = {Tetraoxanes as antimalarials: harnessing the endoperoxide.},
journal = {Mini-Reviews in Medicinal Chemistry},
year = {2014},
volume = {14},
publisher = {Bentham Science Publishers Ltd.},
month = {mar},
url = {https://doi.org/10.2174/1389557514666140123144942},
number = {2},
pages = {123--135},
doi = {10.2174/1389557514666140123144942}
}
Cite this
MLA
Copy
Fisher, Laura. “Tetraoxanes as antimalarials: harnessing the endoperoxide..” Mini-Reviews in Medicinal Chemistry, vol. 14, no. 2, Mar. 2014, pp. 123-135. https://doi.org/10.2174/1389557514666140123144942.