Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review
Тип публикации: Journal Article
Дата публикации: 2017-04-21
scimago Q2
wos Q3
БС1
SJR: 0.662
CiteScore: 8.5
Impact factor: 3.3
ISSN: 13895575, 18755607
PubMed ID:
26471967
Drug Discovery
General Medicine
Pharmacology
Краткое описание
The widespread application of fluorine in drug design benefits from distinctive properties. Incorporation of fluorine can positively modulate certain pharmacokinetics properties, including lipophilicity, eletrophilicity, metabolic stability, chemical stability, et al., which were of interest to medicinal chemists. Herein, fluorinated compounds, which have been designed and evaluated for anticancer, antimicrobial, anti-inflammatory and antivirus activity, et al. during the last 6 years (2010-2015) are summarized.The emphasis is to highlight the importance of fluorinated compounds and the changes in the properties of compounds when introducing fluorine atom.
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MLA
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ГОСТ
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Wang B. et al. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review // Mini-Reviews in Medicinal Chemistry. 2017. Vol. 17. No. 8. pp. 683-692.
ГОСТ со всеми авторами (до 50)
Скопировать
Wang B., Wang L., Jiang B., WANG S., Wu N., Li X., Shi D. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review // Mini-Reviews in Medicinal Chemistry. 2017. Vol. 17. No. 8. pp. 683-692.
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TY - JOUR
DO - 10.2174/1389557515666151016124957
UR - https://doi.org/10.2174/1389557515666151016124957
TI - Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review
T2 - Mini-Reviews in Medicinal Chemistry
AU - Wang, Bao-Cheng
AU - Wang, Lijun
AU - Jiang, Bo
AU - WANG, SHUAI-YU
AU - Wu, Ning
AU - Li, Xiangqian
AU - Shi, Dayong
PY - 2017
DA - 2017/04/21
PB - Bentham Science Publishers Ltd.
SP - 683-692
IS - 8
VL - 17
PMID - 26471967
SN - 1389-5575
SN - 1875-5607
ER -
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BibTex (до 50 авторов)
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@article{2017_Wang,
author = {Bao-Cheng Wang and Lijun Wang and Bo Jiang and SHUAI-YU WANG and Ning Wu and Xiangqian Li and Dayong Shi},
title = {Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review},
journal = {Mini-Reviews in Medicinal Chemistry},
year = {2017},
volume = {17},
publisher = {Bentham Science Publishers Ltd.},
month = {apr},
url = {https://doi.org/10.2174/1389557515666151016124957},
number = {8},
pages = {683--692},
doi = {10.2174/1389557515666151016124957}
}
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MLA
Скопировать
Wang, Bao-Cheng, et al. “Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review.” Mini-Reviews in Medicinal Chemistry, vol. 17, no. 8, Apr. 2017, pp. 683-692. https://doi.org/10.2174/1389557515666151016124957.