Current Cancer Drug Targets

, том 5 , издание 4 , страницы 267-272

Squalamine: a polyvalent drug of the future?

Тип публикации: Journal Article

Дата публикации: 2005-06-01

Bentham Science Publishers Ltd.

Current Cancer Drug Targets

scimago Q2

wos Q2

БС2

SJR: 0.722

CiteScore: 4.1

Impact factor: 3.5

ISSN: 15680096, 18735576

DOI: 10.2174/1568009054064642

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PubMed ID: 15975047

Drug Discovery

Cancer Research

Oncology

Pharmacology

Краткое описание

The purpose of this mini-review is to summarize and highlight the different advances in our understanding of the antimicrobial and antiangiogenic activity of squalamine, a cationic steroid isolated in 1993 from the dogfish shark Squalus Acanthias. Indeed, squalamine has shown to be useful for the treatment of important diseases such as cancers (lung, ovarian, brain and others), age-related macular degeneration (AMD) and the control of body weight in man. All these results led to a question: could we consider squalamine as a polyvalent drug of the future?

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Brunel J. M. et al. Squalamine: a polyvalent drug of the future? // Current Cancer Drug Targets. 2005. Vol. 5. No. 4. pp. 267-272.

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Brunel J. M. Squalamine: a polyvalent drug of the future? // Current Cancer Drug Targets. 2005. Vol. 5. No. 4. pp. 267-272.

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