Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry
Publication type: Journal Article
Publication date: 2016-03-03
scimago Q2
wos Q3
SJR: 0.610
CiteScore: 6.4
Impact factor: 3.3
ISSN: 15680266, 18734294
PubMed ID:
26369815
Drug Discovery
General Medicine
Abstract
The impact of the development of sulfur therapeutics is instrumental to the evolution of the pharmaceutical industry. Sulfur-derived functional groups can be found in a broad range of pharmaceuticals and natural products. For centuries, sulfur continues to maintain its status as the dominating heteroatom integrated into a set of 362 sulfur-containing FDA approved drugs (besides oxygen or nitrogen) through the present. Sulfonamides, thioethers, sulfones and Penicillin are the most common scaffolds in sulfur containing drugs, which are well studied both on synthesis and application during the past decades. In this review, these four moieties in pharmaceuticals and recent advances in the synthesis of the corresponding core scaffolds are presented.
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Total citations:
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(31.91%)
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GOST
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Feng M. et al. Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry // Current Topics in Medicinal Chemistry. 2016. Vol. 16. No. 11. pp. 1200-1216.
GOST all authors (up to 50)
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Jiang X. Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry // Current Topics in Medicinal Chemistry. 2016. Vol. 16. No. 11. pp. 1200-1216.
Cite this
RIS
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TY - JOUR
DO - 10.2174/1568026615666150915111741
UR - https://doi.org/10.2174/1568026615666150915111741
TI - Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry
T2 - Current Topics in Medicinal Chemistry
AU - Jiang, Xuefeng
PY - 2016
DA - 2016/03/03
PB - Bentham Science Publishers Ltd.
SP - 1200-1216
IS - 11
VL - 16
PMID - 26369815
SN - 1568-0266
SN - 1873-4294
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Feng,
author = {Xuefeng Jiang},
title = {Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry},
journal = {Current Topics in Medicinal Chemistry},
year = {2016},
volume = {16},
publisher = {Bentham Science Publishers Ltd.},
month = {mar},
url = {https://doi.org/10.2174/1568026615666150915111741},
number = {11},
pages = {1200--1216},
doi = {10.2174/1568026615666150915111741}
}
Cite this
MLA
Copy
Feng, Minghao, et al. “Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry.” Current Topics in Medicinal Chemistry, vol. 16, no. 11, Mar. 2016, pp. 1200-1216. https://doi.org/10.2174/1568026615666150915111741.
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