Colchicine: A Review on Chemical Structure and Clinical Usage
Тип публикации: Journal Article
Дата публикации: 2017-10-19
scimago Q3
БС2
SJR: 0.288
CiteScore: 3.3
Impact factor: —
ISSN: 18715265, 22123989
PubMed ID:
29046164
General Medicine
Pharmacology
Molecular Medicine
Microbiology (medical)
Краткое описание
For many years, colchicine has been used for therapeutic purposes and has been given considerable attention because of its association with tubulin and inhibition of small tubular polymerization. Colchicine is an alkaloid extracted from the colchicum autumnale plant, having molecular formula C22H25NO6, and consists of three rings. Many studies are concerned with structural changes in order to increase their pharmacological effectiveness and reduce the side effects of toxicity arising from it. The therapeutic use of colchicine has been mainly documented in Gout, Familial Mediterranean Fever, and many other diseases such as atrial fibrillation. This review summarizes the history of chemical structure of colchicine and presents some of its analogues. Furthermore, it shows binding mechanism with target protein when colchicine is used as a therapeutic drug, and gives a light spot on some studies that discuss the safe use of colchicine.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Топ-30
Журналы
|
1
2
3
|
|
|
European Journal of Medicinal Chemistry
3 публикации, 7.14%
|
|
|
Molecules
2 публикации, 4.76%
|
|
|
Bioorganic and Medicinal Chemistry
2 публикации, 4.76%
|
|
|
Tetrahedron Letters
2 публикации, 4.76%
|
|
|
Orthopädie und Unfallchirurgie
2 публикации, 4.76%
|
|
|
Journal of Organic Chemistry
2 публикации, 4.76%
|
|
|
Current Pharmaceutical Design
1 публикация, 2.38%
|
|
|
Trials
1 публикация, 2.38%
|
|
|
Molecular and Cellular Endocrinology
1 публикация, 2.38%
|
|
|
Journal of Surgical Research
1 публикация, 2.38%
|
|
|
Bioorganic Chemistry
1 публикация, 2.38%
|
|
|
Journal of Molecular Liquids
1 публикация, 2.38%
|
|
|
Toxicology in Vitro
1 публикация, 2.38%
|
|
|
Biomedicine and Pharmacotherapy
1 публикация, 2.38%
|
|
|
British Journal of Clinical Pharmacology
1 публикация, 2.38%
|
|
|
Critical Reviews in Food Science and Nutrition
1 публикация, 2.38%
|
|
|
Zeitschrift fur Phytotherapie : offizielles Organ der Ges. f. Phytotherapie e.V
1 публикация, 2.38%
|
|
|
Jundishapur Journal of Natural Pharmaceutical Products
1 публикация, 2.38%
|
|
|
South Russian Journal of Cancer
1 публикация, 2.38%
|
|
|
Current Drug Delivery
1 публикация, 2.38%
|
|
|
Science of the Total Environment
1 публикация, 2.38%
|
|
|
AAPS PharmSciTech
1 публикация, 2.38%
|
|
|
Journal of Functional Biomaterials
1 публикация, 2.38%
|
|
|
Cancer Drug Resistance
1 публикация, 2.38%
|
|
|
Russian Chemical Reviews
1 публикация, 2.38%
|
|
|
Scientia Sinica Chimica
1 публикация, 2.38%
|
|
|
Journal fur Verbraucherschutz und Lebensmittelsicherheit
1 публикация, 2.38%
|
|
|
Drug Discovery Today
1 публикация, 2.38%
|
|
|
Journal of Molecular Structure
1 публикация, 2.38%
|
|
|
1
2
3
|
Издатели
|
2
4
6
8
10
12
14
16
18
|
|
|
Elsevier
18 публикаций, 42.86%
|
|
|
Springer Nature
6 публикаций, 14.29%
|
|
|
MDPI
4 публикации, 9.52%
|
|
|
Bentham Science Publishers Ltd.
3 публикации, 7.14%
|
|
|
American Chemical Society (ACS)
2 публикации, 4.76%
|
|
|
Wiley
1 публикация, 2.38%
|
|
|
Taylor & Francis
1 публикация, 2.38%
|
|
|
Georg Thieme Verlag KG
1 публикация, 2.38%
|
|
|
Brieflands
1 публикация, 2.38%
|
|
|
ANO -Perspective of Oncology
1 публикация, 2.38%
|
|
|
OAE Publishing Inc.
1 публикация, 2.38%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 публикация, 2.38%
|
|
|
Science in China Press
1 публикация, 2.38%
|
|
|
2
4
6
8
10
12
14
16
18
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
42
Всего цитирований:
42
Цитирований c 2025:
8
(19.05%)
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Alkadi H., Khubeiz M. J., Jbeily R. Colchicine: A Review on Chemical Structure and Clinical Usage // Infectious Disorders - Drug Targets. 2017. Vol. 18. No. 2. pp. 105-121.
ГОСТ со всеми авторами (до 50)
Скопировать
Alkadi H., Khubeiz M. J., Jbeily R. Colchicine: A Review on Chemical Structure and Clinical Usage // Infectious Disorders - Drug Targets. 2017. Vol. 18. No. 2. pp. 105-121.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.2174/1871526517666171017114901
UR - https://doi.org/10.2174/1871526517666171017114901
TI - Colchicine: A Review on Chemical Structure and Clinical Usage
T2 - Infectious Disorders - Drug Targets
AU - Alkadi, Hourieh
AU - Khubeiz, Mohamad Jowad
AU - Jbeily, Rajwa
PY - 2017
DA - 2017/10/19
PB - Bentham Science Publishers Ltd.
SP - 105-121
IS - 2
VL - 18
PMID - 29046164
SN - 1871-5265
SN - 2212-3989
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2017_Alkadi,
author = {Hourieh Alkadi and Mohamad Jowad Khubeiz and Rajwa Jbeily},
title = {Colchicine: A Review on Chemical Structure and Clinical Usage},
journal = {Infectious Disorders - Drug Targets},
year = {2017},
volume = {18},
publisher = {Bentham Science Publishers Ltd.},
month = {oct},
url = {https://doi.org/10.2174/1871526517666171017114901},
number = {2},
pages = {105--121},
doi = {10.2174/1871526517666171017114901}
}
Цитировать
MLA
Скопировать
Alkadi, Hourieh, et al. “Colchicine: A Review on Chemical Structure and Clinical Usage.” Infectious Disorders - Drug Targets, vol. 18, no. 2, Oct. 2017, pp. 105-121. https://doi.org/10.2174/1871526517666171017114901.