Designing a system to test for the presence of any nontelomeric nucleotide at the 3′-chromosomal end
Publication type: Journal Article
Publication date: 2016-01-01
scimago Q4
wos Q4
SJR: 0.153
CiteScore: 1.1
Impact factor: 0.5
ISSN: 00271314, 19350260
General Chemistry
Abstract
The number of telomeric repeats in telomeres correlates with the proliferative potential of eukaryotic cells. The lengthening of telomeres and telomerase activity are regulated in several ways. One of these mechanisms is based on the elongation of the 3′-chromasomal end of an additional nucleotide that is not a part of the telomeric repeat motif. This study presents an approach to testing for the presence of an additional nontelomeric nucleotide at the 3′-end of the G strand of chromosomes. The applicability of this method is demonstrated for thermotolerant yeast H. polymorpha. The possibility of modifying the method to test for the presence of an additional nucleotide at the 3′-end of the chromosomes of other organisms is discussed.
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Malyavko A. N. et al. Designing a system to test for the presence of any nontelomeric nucleotide at the 3′-chromosomal end // Moscow University Chemistry Bulletin. 2016. Vol. 71. No. 1. pp. 45-47.
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Malyavko A. N., Petrova O. A., Zvereva M. I., Dontsova O. A. Designing a system to test for the presence of any nontelomeric nucleotide at the 3′-chromosomal end // Moscow University Chemistry Bulletin. 2016. Vol. 71. No. 1. pp. 45-47.
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TY - JOUR
DO - 10.3103/S0027131416010107
UR - http://link.springer.com/10.3103/S0027131416010107
TI - Designing a system to test for the presence of any nontelomeric nucleotide at the 3′-chromosomal end
T2 - Moscow University Chemistry Bulletin
AU - Malyavko, A N
AU - Petrova, O A
AU - Zvereva, M I
AU - Dontsova, O. A.
PY - 2016
DA - 2016/01/01
PB - Allerton Press
SP - 45-47
IS - 1
VL - 71
SN - 0027-1314
SN - 1935-0260
ER -
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@article{2016_Malyavko,
author = {A N Malyavko and O A Petrova and M I Zvereva and O. A. Dontsova},
title = {Designing a system to test for the presence of any nontelomeric nucleotide at the 3′-chromosomal end},
journal = {Moscow University Chemistry Bulletin},
year = {2016},
volume = {71},
publisher = {Allerton Press},
month = {jan},
url = {http://link.springer.com/10.3103/S0027131416010107},
number = {1},
pages = {45--47},
doi = {10.3103/S0027131416010107}
}
Cite this
MLA
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Malyavko, A. N., et al. “Designing a system to test for the presence of any nontelomeric nucleotide at the 3′-chromosomal end.” Moscow University Chemistry Bulletin, vol. 71, no. 1, Jan. 2016, pp. 45-47. http://link.springer.com/10.3103/S0027131416010107.