volume 70 issue 2 pages 67-71

On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams

Publication typeJournal Article
Publication date2015-04-01
scimago Q4
SJR0.161
CiteScore1.1
Impact factor
ISSN00963925, 1934791X
General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences
General Environmental Science
Abstract
A brief comparative analysis of different approaches to cell viability testing in cytogerontological experiments is performed with a focus on problems in constructing survival curves for cultured cells in the “stationary phase aging” model. It is emphasized that the choice of methods to this end depends mainly on the researchers’ ideas about molecular and cellular mechanisms of aging. A note is made that the evaluation of colonyforming efficiency, though optimal for cell viability assessment, is unfortunately not applicable to postmitotic or very slowly propagating cells. Consideration is also given to some problems encountered when using the most popular molecular probes designed for live/dead cell viability assays.
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Khokhlov A. N., Morgunova G. V. On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams // Moscow University Biological Sciences Bulletin. 2015. Vol. 70. No. 2. pp. 67-71.
GOST all authors (up to 50) Copy
Khokhlov A. N., Morgunova G. V. On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams // Moscow University Biological Sciences Bulletin. 2015. Vol. 70. No. 2. pp. 67-71.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3103/S0096392515020054
UR - https://doi.org/10.3103/S0096392515020054
TI - On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams
T2 - Moscow University Biological Sciences Bulletin
AU - Khokhlov, A N
AU - Morgunova, G V
PY - 2015
DA - 2015/04/01
PB - Pleiades Publishing
SP - 67-71
IS - 2
VL - 70
SN - 0096-3925
SN - 1934-791X
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2015_Khokhlov,
author = {A N Khokhlov and G V Morgunova},
title = {On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams},
journal = {Moscow University Biological Sciences Bulletin},
year = {2015},
volume = {70},
publisher = {Pleiades Publishing},
month = {apr},
url = {https://doi.org/10.3103/S0096392515020054},
number = {2},
pages = {67--71},
doi = {10.3103/S0096392515020054}
}
MLA
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MLA Copy
Khokhlov, A. N., and G V Morgunova. “On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams.” Moscow University Biological Sciences Bulletin, vol. 70, no. 2, Apr. 2015, pp. 67-71. https://doi.org/10.3103/S0096392515020054.