Pleiades Publishing
Moscow University Biological Sciences Bulletin
,  том 70 ,  издание 2 ,  страницы 67-71

On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams

Тип публикации: Journal Article
Дата публикации: 2015-04-01
Pleiades Publishing
SCImago Q4
БС2
SJR: 0.161
CiteScore: 1.1
Impact factor: —
ISSN: 00963925, 1934791X
General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences
General Environmental Science
Краткое описание
A brief comparative analysis of different approaches to cell viability testing in cytogerontological experiments is performed with a focus on problems in constructing survival curves for cultured cells in the “stationary phase aging” model. It is emphasized that the choice of methods to this end depends mainly on the researchers’ ideas about molecular and cellular mechanisms of aging. A note is made that the evaluation of colonyforming efficiency, though optimal for cell viability assessment, is unfortunately not applicable to postmitotic or very slowly propagating cells. Consideration is also given to some problems encountered when using the most popular molecular probes designed for live/dead cell viability assays.
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Khokhlov A. N., Morgunova G. V. On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams // Moscow University Biological Sciences Bulletin. 2015. Vol. 70. No. 2. pp. 67-71.
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Khokhlov A. N., Morgunova G. V. On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams // Moscow University Biological Sciences Bulletin. 2015. Vol. 70. No. 2. pp. 67-71.
RIS |
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TY - JOUR
DO - 10.3103/S0096392515020054
UR - https://doi.org/10.3103/S0096392515020054
TI - On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams
T2 - Moscow University Biological Sciences Bulletin
AU - Khokhlov, A N
AU - Morgunova, G V
PY - 2015
DA - 2015/04/01
PB - Pleiades Publishing
SP - 67-71
IS - 2
VL - 70
SN - 0096-3925
SN - 1934-791X
ER -
BibTex |
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@article{2015_Khokhlov,
author = {A N Khokhlov and G V Morgunova},
title = {On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams},
journal = {Moscow University Biological Sciences Bulletin},
year = {2015},
volume = {70},
publisher = {Pleiades Publishing},
month = {apr},
url = {https://doi.org/10.3103/S0096392515020054},
number = {2},
pages = {67--71},
doi = {10.3103/S0096392515020054}
}
MLA
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Khokhlov, A. N., and G V Morgunova. “On the constructing of survival curves for cultured cells in cytogerontological experiments: A brief note with three hierarchy diagrams.” Moscow University Biological Sciences Bulletin, vol. 70, no. 2, Apr. 2015, pp. 67-71. https://doi.org/10.3103/S0096392515020054.
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