Sector of Evolutionary Cytogerontology, Laboratory of Cell Biology of Aging and Development

Testing of some well-known geroprotective drugs that affect the duration and quality of life of model animal objects, as well as some potential geroprotectors, on the cytogerontological model of "stationary aging". The main method of assessment will be the construction of cell culture survival curves in the stationary growth phase and their subsequent analysis, as an additional characteristic, the manifestation of known biomarkers of "cellular age" in cells will be determined. It is proposed to study the effect of several metabolic inhibitors and stressors on the same model system. In some cases, the effect of geroprotectors on non-transplanted cell cultures exposed to stress or inhibitors will be studied.