Moscow University Biological Sciences Bulletin, volume 72, issue 4, pages 222-224

Does Aging Have a Purpose?

Khokhlov A N ¹

Klebanov A A ¹

Morgunova G V ¹

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Evolutionary Cytogerontology Sector, School of Biology, Moscow State University, Moscow, Russia |

Publication type: Journal Article

Publication date: 2017-10-01

Pleiades Publishing

Journal: Moscow University Biological Sciences Bulletin

Quartile SCImago

Quartile WOS

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Impact factor: —

ISSN: 00963925, 1934791X

DOI: 10.3103/S0096392517040058

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General Biochemistry, Genetics and Molecular Biology

General Agricultural and Biological Sciences

General Environmental Science

Abstract

Ideas of proponents and opponents of programmed aging concerning the expediency of this phenomenon for the evolution of living organisms are briefly considered. We think that evolution has no “gerontological” purpose, because the obligate restriction of cell proliferation during the development of multicellular organisms is a factor that “automatically” triggers aging due to the accumulation of various macromolecular lesions in cells as a result of the suppression, or even complete cessation of emergence of new, intact cells. This leads to the “dilution” of stochastic damage (the most important of which is DNA damage) at the level of the entire cellular population. Some additional arguments in favor of the inexpediency of aging for both species and individuals are also listed.

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Moscow University Biological Sciences Bulletin	Moscow University Biological Sciences Bulletin, 5, 83.33% Moscow University Biological Sciences Bulletin 5 publications, 83.33%
Cell Biochemistry and Function	Cell Biochemistry and Function, 1, 16.67% Cell Biochemistry and Function 1 publication, 16.67%
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Pleiades Publishing	Pleiades Publishing, 5, 83.33% Pleiades Publishing 5 publications, 83.33%
Wiley	Wiley, 1, 16.67% Wiley 1 publication, 16.67%
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Khokhlov A. N., Klebanov A. A., Morgunova G. V. Does Aging Have a Purpose? // Moscow University Biological Sciences Bulletin. 2017. Vol. 72. No. 4. pp. 222-224.

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Khokhlov A. N., Klebanov A. A., Morgunova G. V. Does Aging Have a Purpose? // Moscow University Biological Sciences Bulletin. 2017. Vol. 72. No. 4. pp. 222-224.

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