Experimental and Clinical Gastroenterology, volume 1, issue 6, pages 121-129

Precision medicine and inflammatory bowel diseases: concept, strategies, future

Bikbavova G R ¹

Livzan Maria A ¹

Novikov D G ¹

Bambulskaya E A ¹

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Federal State Educational Establishment of Higher Education Omsk State Medical University of the Ministry of Health of the Russian Federation |

Publication type: Journal Article

Publication date: 2021-08-31

Gastroenterological Scientific Society of Russia

Journal: Experimental and Clinical Gastroenterology

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ISSN: 16828658

DOI: 10.31146/1682-8658-ecg-190-6-121-129

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Gastroenterology

Hepatology

Abstract

With the advent of modern cellular and genomic technologies, we have become participants in the integration of such areas as personalized, predictive, preventive, and precision medicine (referred to as 4P-medicine), into practical healthcare. In replace of the classic methods of diagnosis and treatment of diseases comes medicine, which makes it possible to predict (anticipate) the disease, and a personalized approach to each patient, taking into account their genetic, biochemical and physiological uniqueness. Precision medicine aims to improve the quality of medical care by opening up an individual approach to the patient and covers a wide range of areas, including drug therapy, genetics, and cause-and-effect relationships in order to make the right decisions based on evidence. 4P-medicine combines knowledge in the field of proteomics, metabolomics, genomics, bioinformatics with classical approaches of anatomy, therapy, laboratory and instrumental diagnostics as well as public health. The purpose of this review is to analyze and summarize the information available to date and to present examples of the application of modern approaches of medicine into clinical practice by diving into the example of inflammatory bowel diseases (IBD). The search for literature containing scientific information about relevant studies was conducted in the PubMed and Google Scholar systems with the use of the following keywords: precision medicine, 4P medicine, inflammatory bowel diseases. Despite significant progress in medicine in general, there is still a long way to go before implementing the principles of precision medicine in the field of IBD, since many clinicians continue to treat patients with IBD symptomatically. However, the use of specific biomarkers and new treatment strategies as described in the review, can significantly accelerate this path and contribute to the improvement of diagnostic and therapeutic approaches.

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Bikbavova G. R. et al. Precision medicine and inflammatory bowel diseases: concept, strategies, future // Experimental and Clinical Gastroenterology. 2021. Vol. 1. No. 6. pp. 121-129.

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Bikbavova G. R., Livzan M. A., Novikov D. G., Bambulskaya E. A. Precision medicine and inflammatory bowel diseases: concept, strategies, future // Experimental and Clinical Gastroenterology. 2021. Vol. 1. No. 6. pp. 121-129.

RIS |

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RIS Copy

TY - JOUR

DO - 10.31146/1682-8658-ecg-190-6-121-129

UR - https://doi.org/10.31146%2F1682-8658-ecg-190-6-121-129

TI - Precision medicine and inflammatory bowel diseases: concept, strategies, future

T2 - Experimental and Clinical Gastroenterology

AU - Bikbavova, G R

AU - Livzan, Maria A

AU - Novikov, D G

AU - Bambulskaya, E A

PY - 2021

DA - 2021/08/31 00:00:00

PB - Gastroenterological Scientific Society of Russia

SP - 121-129

IS - 6

VL - 1

SN - 1682-8658

ER -

BibTex |

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@article{2021_Bikbavova,

author = {G R Bikbavova and Maria A Livzan and D G Novikov and E A Bambulskaya},

title = {Precision medicine and inflammatory bowel diseases: concept, strategies, future},

journal = {Experimental and Clinical Gastroenterology},

year = {2021},

volume = {1},

publisher = {Gastroenterological Scientific Society of Russia},

month = {aug},

url = {https://doi.org/10.31146%2F1682-8658-ecg-190-6-121-129},

number = {6},

pages = {121--129},

doi = {10.31146/1682-8658-ecg-190-6-121-129}

}

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Bikbavova, G. R., et al. “Precision medicine and inflammatory bowel diseases: concept, strategies, future.” Experimental and Clinical Gastroenterology, vol. 1, no. 6, Aug. 2021, pp. 121-129. https://doi.org/10.31146%2F1682-8658-ecg-190-6-121-129.

Found error?

Publisher

Gastroenterological Scientific Society of Russia

Journal

Experimental and Clinical Gastroenterology

Quartile SCImago

Quartile WOS

—

Impact factor

—

ISSN

16828658 (Print)

Labs

Central Research Laboratory

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