Open Access
,
volume 12
The Role of Short-Chain Fatty Acids of Gut Microbiota Origin in Hypertension
Publication type: Journal Article
Publication date: 2021-09-28
scimago Q1
wos Q1
SJR: 1.172
CiteScore: 8.5
Impact factor: 4.5
ISSN: 1664302X
PubMed ID:
34650536
Microbiology (medical)
Microbiology
Abstract
Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases, and its development involves multiple mechanisms. Gut microbiota has been reported to be closely linked to hypertension. Short-chain fatty acids (SCFAs)—the metabolites of gut microbiota—participate in hypertension development through various pathways, including specific receptors, immune system, autonomic nervous system, metabolic regulation and gene transcription. This article reviews the possible mechanisms of SCFAs in regulating blood pressure and the prospects of SCFAs as a target to prevent and treat hypertension.
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Metrics
85
Total citations:
85
Citations from 2024:
44
(51.77%)
Cite this
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RIS |
BibTex
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GOST
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Wu Y. et al. The Role of Short-Chain Fatty Acids of Gut Microbiota Origin in Hypertension // Frontiers in Microbiology. 2021. Vol. 12.
GOST all authors (up to 50)
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Wu Y., Xu H., Tu X., Gao Z. The Role of Short-Chain Fatty Acids of Gut Microbiota Origin in Hypertension // Frontiers in Microbiology. 2021. Vol. 12.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3389/fmicb.2021.730809
UR - https://doi.org/10.3389/fmicb.2021.730809
TI - The Role of Short-Chain Fatty Acids of Gut Microbiota Origin in Hypertension
T2 - Frontiers in Microbiology
AU - Wu, Yeshun
AU - Xu, Hongqing
AU - Tu, Xiaoming
AU - Gao, Zhenyan
PY - 2021
DA - 2021/09/28
PB - Frontiers Media S.A.
VL - 12
PMID - 34650536
SN - 1664-302X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Wu,
author = {Yeshun Wu and Hongqing Xu and Xiaoming Tu and Zhenyan Gao},
title = {The Role of Short-Chain Fatty Acids of Gut Microbiota Origin in Hypertension},
journal = {Frontiers in Microbiology},
year = {2021},
volume = {12},
publisher = {Frontiers Media S.A.},
month = {sep},
url = {https://doi.org/10.3389/fmicb.2021.730809},
doi = {10.3389/fmicb.2021.730809}
}