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Journal of Personalized Medicine, volume 11, issue 4, pages 294

Gut Microbiome in a Russian Cohort of Pre- and Post-Cholecystectomy Female Patients

Grigoreva Irina ¹

Romanova Tatyana I ¹

Naumova Natalia ²

Alikina Tatiana ²

Kuznetsov Alexey ³

Kabilov Marsel R. ²

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Research Institute of Internal and Preventive Medicine—Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630089, Russia

Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences

Institute of Internal and Preventive Medicine ICG of the Siberian Branch of the Russian Academy of Sciences

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia |

Novosibirsk State Medical University, Novosibirsk 630091, Russia |

Publication type: Journal Article

Publication date: 2021-04-12

Multidisciplinary Digital Publishing Institute (MDPI)

Journal: Journal of Personalized Medicine

Quartile SCImago

Quartile WOS

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Impact factor: —

ISSN: 20754426

DOI: 10.3390/jpm11040294

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Medicine (miscellaneous)

Abstract

The last decade saw extensive studies of the human gut microbiome and its relationship to specific diseases, including gallstone disease (GSD). The information about the gut microbiome in GSD-afflicted Russian patients is scarce, despite the increasing GSD incidence worldwide. Although the gut microbiota was described in some GSD cohorts, little is known regarding the gut microbiome before and after cholecystectomy (CCE). By using Illumina MiSeq sequencing of 16S rRNA gene amplicons, we inventoried the fecal bacteriobiome composition and structure in GSD-afflicted females, seeking to reveal associations with age, BMI and some blood biochemistry. Overall, 11 bacterial phyla were identified, containing 916 operational taxonomic units (OTUs). The fecal bacteriobiome was dominated by Firmicutes (66% relative abundance), followed by Bacteroidetes (19%), Actinobacteria (8%) and Proteobacteria (4%) phyla. Most (97%) of the OTUs were minor or rare species with ≤1% relative abundance. Prevotella and Enterocossus were linked to blood bilirubin. Some taxa had differential pre- and post-CCE abundance, despite the very short time (1–3 days) elapsed after CCE. The detailed description of the bacteriobiome in pre-CCE female patients suggests bacterial foci for further research to elucidate the gut microbiota and GSD relationship and has potentially important biological and medical implications regarding gut bacteria involvement in the increased GSD incidence rate in females.

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Citations by journals

	1 2
World Journal of Gastroenterology	World Journal of Gastroenterology, 2, 25% World Journal of Gastroenterology 2 publications, 25%
Journal of Personalized Medicine	Journal of Personalized Medicine, 1, 12.5% Journal of Personalized Medicine 1 publication, 12.5%
European Journal of Nutrition	European Journal of Nutrition, 1, 12.5% European Journal of Nutrition 1 publication, 12.5%
Russian Journal of Cardiology	Russian Journal of Cardiology, 1, 12.5% Russian Journal of Cardiology 1 publication, 12.5%
International Journal of Surgery	International Journal of Surgery, 1, 12.5% International Journal of Surgery 1 publication, 12.5%
	1 2

Citations by publishers

	1 2
Baishideng Publishing Group	Baishideng Publishing Group, 2, 25% Baishideng Publishing Group 2 publications, 25%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 1, 12.5% Multidisciplinary Digital Publishing Institute (MDPI) 1 publication, 12.5%
Springer Nature	Springer Nature, 1, 12.5% Springer Nature 1 publication, 12.5%
Russian Society of Cardiology	Russian Society of Cardiology, 1, 12.5% Russian Society of Cardiology 1 publication, 12.5%
Elsevier	Elsevier, 1, 12.5% Elsevier 1 publication, 12.5%
	1 2

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Grigoreva I. et al. Gut Microbiome in a Russian Cohort of Pre- and Post-Cholecystectomy Female Patients // Journal of Personalized Medicine. 2021. Vol. 11. No. 4. p. 294.

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Grigoreva I., Romanova T. I., Naumova N., Alikina T., Kuznetsov A., Kabilov M. R. Gut Microbiome in a Russian Cohort of Pre- and Post-Cholecystectomy Female Patients // Journal of Personalized Medicine. 2021. Vol. 11. No. 4. p. 294.

RIS |

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RIS Copy

TY - JOUR

DO - 10.3390/jpm11040294

UR - https://doi.org/10.3390%2Fjpm11040294

TI - Gut Microbiome in a Russian Cohort of Pre- and Post-Cholecystectomy Female Patients

T2 - Journal of Personalized Medicine

AU - Naumova, Natalia

AU - Alikina, Tatiana

AU - Kuznetsov, Alexey

AU - Grigoreva, Irina

AU - Romanova, Tatyana I

AU - Kabilov, Marsel R.

PY - 2021

DA - 2021/04/12 00:00:00

PB - Multidisciplinary Digital Publishing Institute (MDPI)

SP - 294

IS - 4

VL - 11

SN - 2075-4426

ER -

BibTex |

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BibTex Copy

@article{2021_Grigoreva,

author = {Natalia Naumova and Tatiana Alikina and Alexey Kuznetsov and Irina Grigoreva and Tatyana I Romanova and Marsel R. Kabilov},

title = {Gut Microbiome in a Russian Cohort of Pre- and Post-Cholecystectomy Female Patients},

journal = {Journal of Personalized Medicine},

year = {2021},

volume = {11},

publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},

month = {apr},

url = {https://doi.org/10.3390%2Fjpm11040294},

number = {4},

pages = {294},

doi = {10.3390/jpm11040294}

}

MLA

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Grigoreva, Irina, et al. “Gut Microbiome in a Russian Cohort of Pre- and Post-Cholecystectomy Female Patients.” Journal of Personalized Medicine, vol. 11, no. 4, Apr. 2021, p. 294. https://doi.org/10.3390%2Fjpm11040294.

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