Open Access

Polymers

, volume 16 , issue 2 , pages 287

Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials

Galina A Davydova ¹

Leonid L Chaikov ²

Nikolay Melnik ²

R.V. Gainutdinov ³

Irina I. Selezneva ¹

Elena Perevedentseva ²

Muhriddin T. Mahamadiev ²

Vadim A. Proskurin ⁴

Daniel S. Yakovsky ⁵

Aurel George Mohan ^{6, 7}

Julietta V. Rau ^{8, 9}

Hide authors affiliations Show authors affiliations: 9 affiliations

Federal State Institution of Science Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences (ITEB RAS), Institutskaya St., 3, Pushchino 142290, Moscow Region, Russia |

Federal State Budgetary Institution of Science P.N. Lebedev Physical Institute, Russian Academy of Sciences, Leninsky Prospekt, 53, GSP-1, Moscow 119991, Russia |

Federal Research Centre “Crystallography and Photonics” of the Russian Academy of Sciences, Leninsky Prospekt, 59, Moscow 119333, Russia |

⁴

Pushchino Branch of Federal State Budgetary Educational Institution of Higher Education “Russian Biotechnology University (ROSBIOTECH)”, Nauki Ave. 3, Pushchino 142290, Moscow Region, Russia |

⁵

Department of Biotechnology, Institute of Natural Science, Federal State Budgetary Educational Institution of Higher Education “Tula State University”, Lenin Ave. 92, 9th Academic Building, Tula 300012, Russia |

⁶

Faculty of Medicine and Pharmacy, University of Oradea, 10 P-ta 1 December Street, 410073 Oradea, Romania |

⁷

Department of Neurosurgery, Clinical Emergency Hospital Oradea, 65 Gheorghe Doja Street, 410169 Oradea, Romania |

⁸

Istituto di Struttura Della Materia, Consiglio Nazionale Delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, Italy |

⁹

Department of Analytical, Physical and Colloid Chemistry, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Trubetskaya 8, Build. 2, Moscow 119048, Russia |

Publication type: Journal Article

Publication date: 2024-01-20

MDPI

Polymers

scimago Q1

wos Q1

SJR: 0.918

CiteScore: 9.7

Impact factor: 4.9

ISSN: 20734360

DOI: 10.3390/polym16020287

Copy DOI

PubMed ID: 38276695

General Chemistry

Polymers and Plastics

Abstract

This article presents materials that highlight the bioengineering potential of polymeric systems of natural origin based on biodegradable polysaccharides, with applications in creating modern products for localized wound healing. Exploring the unique biological and physicochemical properties of polysaccharides offers a promising avenue for the atraumatic, controlled restoration of damaged tissues in extensive wounds. The study focused on alginate, pectin, and a hydrogel composed of their mixture in a 1:1 ratio. Atomic force microscopy data revealed that the two-component gel exhibits greater cohesion and is characterized by the presence of filament-like elements. The dynamic light scattering method indicated that this structural change results in a reduction in the damping of acoustic modes in the gel mixture compared to the component gels. Raman spectroscopy research on these gels revealed the emergence of new bonds between the components’ molecules, contributing to the observed effects. The biocompatibility of the gels was evaluated using dental pulp stem cells, demonstrating that all the gels exhibit biocompatibility.

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GOST Copy

Davydova G. A. et al. Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials // Polymers. 2024. Vol. 16. No. 2. p. 287.

GOST all authors (up to 50) Copy

Davydova G. A., Chaikov L. L., Melnik N., Gainutdinov R., Selezneva I. I., Perevedentseva E., Mahamadiev M. T., Proskurin V. A., Yakovsky D. S., Mohan A. G., Rau J. V. Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials // Polymers. 2024. Vol. 16. No. 2. p. 287.

RIS |

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RIS Copy

TY - JOUR

DO - 10.3390/polym16020287

UR - https://www.mdpi.com/2073-4360/16/2/287

TI - Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials

T2 - Polymers

AU - Davydova, Galina A

AU - Chaikov, Leonid L

AU - Melnik, Nikolay

AU - Gainutdinov, R.V.

AU - Selezneva, Irina I.

AU - Perevedentseva, Elena

AU - Mahamadiev, Muhriddin T.

AU - Proskurin, Vadim A.

AU - Yakovsky, Daniel S.

AU - Mohan, Aurel George

AU - Rau, Julietta V.

PY - 2024

DA - 2024/01/20

PB - MDPI

SP - 287

IS - 2

VL - 16

PMID - 38276695

SN - 2073-4360

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2024_Davydova,

author = {Galina A Davydova and Leonid L Chaikov and Nikolay Melnik and R.V. Gainutdinov and Irina I. Selezneva and Elena Perevedentseva and Muhriddin T. Mahamadiev and Vadim A. Proskurin and Daniel S. Yakovsky and Aurel George Mohan and Julietta V. Rau},

title = {Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials},

journal = {Polymers},

year = {2024},

volume = {16},

publisher = {MDPI},

month = {jan},

url = {https://www.mdpi.com/2073-4360/16/2/287},

number = {2},

pages = {287},

doi = {10.3390/polym16020287}

}

MLA

Cite this

MLA Copy

Davydova, Galina A., et al. “Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials.” Polymers, vol. 16, no. 2, Jan. 2024, p. 287. https://www.mdpi.com/2073-4360/16/2/287.

Publisher

MDPI

Journal

Polymers

scimago Q1

wos Q1

SJR

0.918

CiteScore

9.7

Impact factor

4.9

ISSN

20734360 (Electronic)

Labs

Laboratory of Cell and Tissue Growth

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