Open Access
Viruses, volume 14, issue 2, pages 437
Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus
Prokhorova Daria
1, 2
,
Zhukova (eschenko) Natalya
1
,
Lemza Anna
1
,
Sergeeva Maria V
1, 3
,
Amirkhanov Rinat
1
,
Publication type: Journal Article
Publication date: 2022-02-21
PubMed ID:
35216030
Infectious Diseases
Virology
Abstract
Influenza A virus (IAV) causes a respiratory infection that affects millions of people of different age groups and can lead to acute respiratory distress syndrome. Currently, host genes, receptors, and other cellular components critical for IAV replication are actively studied. One of the most convenient and accessible genome-editing tools to facilitate these studies is the CRISPR/Cas9 system. This tool allows for regulating the expression of both viral and host cell genes to enhance or impair viral entry and replication. This review considers the effect of the genome editing system on specific target genes in cells (human and chicken) in terms of subsequent changes in the influenza virus life cycle and the efficiency of virus particle production.
Citations by journals
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1
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International Journal of Molecular Sciences
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International Journal of Molecular Sciences
1 publication, 33.33%
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Food Control
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Food Control
1 publication, 33.33%
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1
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Citations by publishers
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1
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 33.33%
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Elsevier
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Elsevier
1 publication, 33.33%
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1
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Prokhorova D. et al. Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus // Viruses. 2022. Vol. 14. No. 2. p. 437.
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Prokhorova D., Zhukova (eschenko) N., Lemza A., Sergeeva M. V., Amirkhanov R., Stepanov G. A. Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus // Viruses. 2022. Vol. 14. No. 2. p. 437.
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TY - JOUR
DO - 10.3390/v14020437
UR - https://doi.org/10.3390%2Fv14020437
TI - Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus
T2 - Viruses
AU - Prokhorova, Daria
AU - Zhukova (eschenko), Natalya
AU - Lemza, Anna
AU - Amirkhanov, Rinat
AU - Sergeeva, Maria V
AU - Stepanov, Grigory A
PY - 2022
DA - 2022/02/21 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 437
IS - 2
VL - 14
PMID - 35216030
SN - 1999-4915
ER -
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@article{2022_Prokhorova,
author = {Daria Prokhorova and Natalya Zhukova (eschenko) and Anna Lemza and Rinat Amirkhanov and Maria V Sergeeva and Grigory A Stepanov},
title = {Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus},
journal = {Viruses},
year = {2022},
volume = {14},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {feb},
url = {https://doi.org/10.3390%2Fv14020437},
number = {2},
pages = {437},
doi = {10.3390/v14020437}
}
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MLA
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Prokhorova, Daria, et al. “Application of the CRISPR/Cas9 System to Study Regulation Pathways of the Cellular Immune Response to Influenza Virus.” Viruses, vol. 14, no. 2, Feb. 2022, p. 437. https://doi.org/10.3390%2Fv14020437.
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